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Oxybutynin

Prescription
Anticholinergic / Antispasmodic (Urinary)
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
4

Mechanism of action

Direct smooth muscle relaxant with anticholinergic (antimuscarinic M3) properties that reduces detrusor muscle contractions and increases bladder capacity. Used for urge incontinence and detrusor hyperreflexia.

At a glance

Class
Anticholinergic / Antispasmodic (Urinary)
Schedule
Prescription
Storage
Store at room temperature below 30°C

Dosing

🐕

Dog

Used for urge incontinence, detrusor instability, and reflex dyssynergia
Dose
1.25–5 mg/dog
Route
PO
Frequency
q8–12h
🐈

Cat

Used for feline lower urinary tract disease with detrusor instability
Dose
0.5–1.25 mg/cat
Route
PO
Frequency
q8–12h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 4

Strength
Strength
Strength
Strength

Storage

Store at room temperature below 30°C

Safety

Monitoring parameters

Urinary frequency/incontinence episodesUrine output (retention)GI motilityHeart rate
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Ditropan

FAQs

Frequently asked questions

What is Oxybutynin?
Oxybutynin is a anticholinergic / antispasmodic (urinary) used in pets. Direct smooth muscle relaxant with anticholinergic (antimuscarinic M3) properties that reduces detrusor muscle contractions and increases bladder capacity. Used for urge incontinence and detrusor hyperreflexia.
What is Oxybutynin used for in pets?
Oxybutynin is used in veterinary medicine for: Used for urge incontinence, detrusor instability, and reflex dyssynergia; Used for feline lower urinary tract disease with detrusor instability.
What is the Oxybutynin dose for dogs?
For dogs, Oxybutynin is typically dosed as follows — Used for urge incontinence, detrusor instability, and reflex dyssynergia: 1.25–5 mg/dog PO q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Oxybutynin dose for cats?
For cats, Oxybutynin is typically dosed as follows — Used for feline lower urinary tract disease with detrusor instability: 0.5–1.25 mg/cat PO q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Oxybutynin need a prescription?
Yes. Oxybutynin is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Anticholinergic / Antispasmodic).

Butylscopolamine
Rx
Quaternary ammonium derivative of scopolamine that does not cross the blood-brain barrier. Competitively blocks muscarinic acetylcholine receptors in smooth muscle, reducing GI, urinary, and biliary spasms.
dogcat
Hyoscyamine
Rx
L-isomer of atropine with potent anticholinergic activity at muscarinic receptors in smooth muscle, secretory glands, and the CNS. Reduces GI motility and secretions, bladder spasm, and bronchial secretions. Twice as potent as racemic atropine per mg.
dogcat
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