Quaternary ammonium derivative of scopolamine that does not cross the blood-brain barrier. Competitively blocks muscarinic acetylcholine receptors in smooth muscle, reducing GI, urinary, and biliary spasms.
At a glance
Class
Anticholinergic / Antispasmodic
Storage
Store at room temperature, protect from light
Dosing
Used for GI spasm, biliary colic, and renal colic
Used for feline lower urinary tract spasm and GI cramping
Safety
Heart rateUrine outputGI motility
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Butylscopolamine?
Butylscopolamine is a anticholinergic / antispasmodic used in pets. Quaternary ammonium derivative of scopolamine that does not cross the blood-brain barrier. Competitively blocks muscarinic acetylcholine receptors in smooth muscle, reducing GI, urinary, and biliary spasms.
›What is Butylscopolamine used for in pets?
Butylscopolamine is used in veterinary medicine for: Used for GI spasm, biliary colic, and renal colic; Used for feline lower urinary tract spasm and GI cramping.
›What is the Butylscopolamine dose for dogs?
For dogs, Butylscopolamine is typically dosed as follows — Used for GI spasm, biliary colic, and renal colic: 0.3–0.5 mg/kg IM/SQ/IV/PO q6–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Butylscopolamine dose for cats?
For cats, Butylscopolamine is typically dosed as follows — Used for feline lower urinary tract spasm and GI cramping: 0.1–0.3 mg/kg IM/SQ q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Butylscopolamine need a prescription?
Yes. Butylscopolamine is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →