Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription. Bactericidal activity against a wide range of gram-positive and gram-negative ocular pathogens.
At a glance
Class
Fluoroquinolone Antibiotic (Ophthalmic)
Storage
Store at room temperature; discard 28 days after opening
Dosing
Used for bacterial conjunctivitis, corneal ulcers (bacterial), and keratitis
Frequency
q2–6h depending on severity
Effective for most feline bacterial conjunctivitis
Safety
Corneal healing responseSigns of fungal superinfection with prolonged use
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Ofloxacin (Ophthalmic)?
Ofloxacin (Ophthalmic) is a fluoroquinolone antibiotic (ophthalmic) used in pets. Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription. Bactericidal activity against a wide range of gram-positive and gram-negative ocular pathogens.
›What is Ofloxacin (Ophthalmic) used for in pets?
Ofloxacin (Ophthalmic) is used in veterinary medicine for: Used for bacterial conjunctivitis, corneal ulcers (bacterial), and keratitis; Effective for most feline bacterial conjunctivitis.
›What is the Ofloxacin (Ophthalmic) dose for dogs?
For dogs, Ofloxacin (Ophthalmic) is typically dosed as follows — Used for bacterial conjunctivitis, corneal ulcers (bacterial), and keratitis: undefined undefined Ophthalmic q2–6h depending on severity. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Ofloxacin (Ophthalmic) dose for cats?
For cats, Ofloxacin (Ophthalmic) is typically dosed as follows — Effective for most feline bacterial conjunctivitis: undefined undefined Ophthalmic q4–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Ofloxacin (Ophthalmic) need a prescription?
Yes. Ofloxacin (Ophthalmic) is a prescription medication and should only be administered under veterinary supervision.
References
CDSCO approvals (India) — 1
Danofloxacin Mesylate injection
M/s Pfizer Limited · Approved 12.08.1995
Bovine respiratory disease in beef cattle non lactating dairy cattle calves caused by pasteurella haemolytica p multocid
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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