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Ofloxacin (Ophthalmic)

Prescription
Fluoroquinolone Antibiotic (Ophthalmic)
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
1

Mechanism of action

Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription. Bactericidal activity against a wide range of gram-positive and gram-negative ocular pathogens.

At a glance

Class
Fluoroquinolone Antibiotic (Ophthalmic)
Schedule
Prescription
Storage
Store at room temperature; discard 28 days after opening

Dosing

🐕

Dog

Used for bacterial conjunctivitis, corneal ulcers (bacterial), and keratitis
Dose
Route
Ophthalmic
Frequency
q2–6h depending on severity
🐈

Cat

Effective for most feline bacterial conjunctivitis
Dose
Route
Ophthalmic
Frequency
q4–6h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature; discard 28 days after opening

Safety

Monitoring parameters

Corneal healing responseSigns of fungal superinfection with prolonged use
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Ocuflox
Exocin

FAQs

Frequently asked questions

What is Ofloxacin (Ophthalmic)?
Ofloxacin (Ophthalmic) is a fluoroquinolone antibiotic (ophthalmic) used in pets. Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription. Bactericidal activity against a wide range of gram-positive and gram-negative ocular pathogens.
What is Ofloxacin (Ophthalmic) used for in pets?
Ofloxacin (Ophthalmic) is used in veterinary medicine for: Used for bacterial conjunctivitis, corneal ulcers (bacterial), and keratitis; Effective for most feline bacterial conjunctivitis.
What is the Ofloxacin (Ophthalmic) dose for dogs?
For dogs, Ofloxacin (Ophthalmic) is typically dosed as follows — Used for bacterial conjunctivitis, corneal ulcers (bacterial), and keratitis: undefined undefined Ophthalmic q2–6h depending on severity. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Ofloxacin (Ophthalmic) dose for cats?
For cats, Ofloxacin (Ophthalmic) is typically dosed as follows — Effective for most feline bacterial conjunctivitis: undefined undefined Ophthalmic q4–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Ofloxacin (Ophthalmic) need a prescription?
Yes. Ofloxacin (Ophthalmic) is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

CDSCO approvals (India) — 1

Danofloxacin Mesylate injection
M/s Pfizer Limited · Approved 12.08.1995
Bovine respiratory disease in beef cattle non lactating dairy cattle calves caused by pasteurella haemolytica p multocid
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Fluoroquinolone Antibiotic).

Ciprofloxacin (Ophthalmic)
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Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication; broad-spectrum activity against ocular pathogens
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Enrofloxacin
Rx
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication
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Marbofloxacin
Rx
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription
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