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Ciprofloxacin (Ophthalmic)

Prescription
Fluoroquinolone antibiotic (ophthalmic)
Last reviewed 19 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
3 available
Formulations
2

Mechanism of action

Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication; broad-spectrum activity against ocular pathogens

At a glance

Class
Fluoroquinolone antibiotic (ophthalmic)
Schedule
Prescription
Storage
Store below 25°C, protect from light

Dosing

🐕

Dog

Bacterial conjunctivitis / Corneal ulcer (superficial, non-melting)
Dose
0 mg/kg
Route
Ophthalmic
Frequency
QID (q4–6h); hourly for first 24–48h in severe ulcers
Max dose
0 mg
Duration: 7–14 days; continue 48h past resolution
🐈

Cat

Bacterial conjunctivitis / Secondary bacterial infection
Dose
0 mg/kg
Route
Ophthalmic
Frequency
QID
Max dose
0 mg
Duration: 7–14 days
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

🧴

Ophthalmic solution — 1

Strength
0.3%
Available in India
🧪

Ophthalmic ointment — 1

Strength
0.3%
Available in India

Storage

Store below 25°C, protect from light

Safety

Use with caution

  • Fluoroquinolone hypersensitivity
  • Fungal or viral keratitis
    Antibiotic may delay diagnosis

Adverse effects

Common
Transient ocular stinging
White corneal precipitate (crystalline deposits)
Serious
Corneal toxicity (rare with prolonged use)

Monitoring parameters

Clinical responseFluorescein stainingCorneal health
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

International

Ciloxan
Alcon

India

Ciplox Eye
Cipla
Zoxan-D
FDC Limited

FAQs

Frequently asked questions

What is Ciprofloxacin (Ophthalmic)?
Ciprofloxacin (Ophthalmic) is a fluoroquinolone antibiotic (ophthalmic) used in pets. Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication; broad-spectrum activity against ocular pathogens
What is Ciprofloxacin (Ophthalmic) used for in pets?
Ciprofloxacin (Ophthalmic) is used in veterinary medicine for: Bacterial conjunctivitis / Corneal ulcer (superficial, non-melting); Bacterial conjunctivitis / Secondary bacterial infection.
What is the Ciprofloxacin (Ophthalmic) dose for dogs?
For dogs, Ciprofloxacin (Ophthalmic) is typically dosed as follows — Bacterial conjunctivitis / Corneal ulcer (superficial, non-melting): 0 mg/kg Ophthalmic QID (q4–6h); hourly for first 24–48h in severe ulcers. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Ciprofloxacin (Ophthalmic) dose for cats?
For cats, Ciprofloxacin (Ophthalmic) is typically dosed as follows — Bacterial conjunctivitis / Secondary bacterial infection: 0 mg/kg Ophthalmic QID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What are the side effects of Ciprofloxacin (Ophthalmic)?
Common: Transient ocular stinging, White corneal precipitate (crystalline deposits). Serious (call your vet immediately): Corneal toxicity (rare with prolonged use).
Does Ciprofloxacin (Ophthalmic) need a prescription?
Yes. Ciprofloxacin (Ophthalmic) is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Fluoroquinolone antibiotic).

Enrofloxacin
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Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication
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Marbofloxacin
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Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription
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Ofloxacin (Ophthalmic)
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Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription. Bactericidal activity against a wide range of gram-positive and gram-negative ocular pathogens.
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