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Marbofloxacin

PrescriptionCDSCO approved

Fluoroquinolone antibiotic

Last reviewed 19 Apr 2026 · PetCare.AI Editorial Team

Species

Dog, Cat

Brands

3 available

Interactions

1 documented

Formulations

Mechanism of action

Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription

At a glance

Class

Fluoroquinolone antibiotic

Schedule

Prescription

Storage

Store below 25°C

CDSCO (India)

Vet-approved — 2005-01

Dosing

🐕

Dog

Skin infections

Dose

2–5.5 mg/kg

Route

Frequency

SID

Max dose

200 mg

Duration: 14-28 days

Urinary tract infections

Dose

2–5.5 mg/kg

Route

Frequency

SID

Max dose

200 mg

Duration: 10-14 days

🐈

Cat

Skin and urinary infections

Dose

2–5.5 mg/kg

Route

Frequency

SID

Max dose

50 mg

Duration: 7-14 days

Educational reference only

This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Tablet — 3

Strength

5mg

Available in India

Strength

20mg

Available in India

Strength

80mg

Available in India

💉

Injectable — 1

Strength

20mg/mL

Available in India

Storage

Store below 25°C

Safety

Absolute contraindications — do not use

Growing animals
Avoid in puppies <12 months and kittens <8 weeks — cartilage damage

Use with caution

Seizure disorders
Lowers seizure threshold
Dehydration
Risk of crystalluria — ensure adequate hydration

Adverse effects

Common

Vomiting

Soft stools

Decreased appetite

Serious

Cartilage erosion in young animals

Seizures

Retinal toxicity in cats (high doses)

Monitoring parameters

Joint health in young animalsNeurological signsHydration

Educational reference only

Interactions

Moderate — 1

Sucralfate

moderate

Sucralfate (aluminum-containing) chelates fluoroquinolones, reducing absorption by 50-90%.

Management: Separate by 2 hours. Give marbofloxacin 2h before or 4h after sucralfate.

Educational reference only

Brands

International

Marbocyl

Vetoquinol

Zeniquin

Zoetis

India

Marbomet

Intas

FAQs

Frequently asked questions

›What is Marbofloxacin?

Marbofloxacin is a fluoroquinolone antibiotic used in pets. Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription

›What is Marbofloxacin used for in pets?

Marbofloxacin is used in veterinary medicine for: Skin infections; Urinary tract infections; Skin and urinary infections.

›What is the Marbofloxacin dose for dogs?

For dogs, Marbofloxacin is typically dosed as follows — Skin infections: 2–5.5 mg/kg PO SID; Urinary tract infections: 2–5.5 mg/kg PO SID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.

›What is the Marbofloxacin dose for cats?

For cats, Marbofloxacin is typically dosed as follows — Skin and urinary infections: 2–5.5 mg/kg PO SID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.

›What are the side effects of Marbofloxacin?

Common: Vomiting, Soft stools, Decreased appetite. Serious (call your vet immediately): Cartilage erosion in young animals, Seizures, Retinal toxicity in cats (high doses).

›Does Marbofloxacin need a prescription?

Yes. Marbofloxacin is a prescription medication and should only be administered under veterinary supervision.

›When should Marbofloxacin not be used?

Do not use Marbofloxacin if: Growing animals.

Educational reference only