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Imidocarb Dipropionate

Prescription
Antiprotozoal (Carbanilide Derivative)
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Binds to DNA minor groove and inhibits polyamine synthesis in protozoa, disrupting nucleic acid metabolism. Also concentrates in liver and kidney of protozoa, interfering with aerobic glycolysis. Active against Babesia, Hepatozoon, and Ehrlichia.

At a glance

Class
Antiprotozoal (Carbanilide Derivative)
Schedule
Prescription
Storage
Store at room temperature below 25°C, protect from light

Dosing

🐕

Dog

Treatment of choice for Babesia canis (large Babesia)
Dose
5–6 mg/kg
Route
IM, SQ
Frequency
Once or q14 days x 2–3 doses
🐈

Cat

Off-label for feline babesiosis and cytauxzoonosis
Dose
3.5 mg/kg
Route
IM
Frequency
Once
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature below 25°C, protect from light

Safety

Monitoring parameters

Pre-treat with atropineObserve 30 min post-injection for cholinergic signsHepatic and renal functionBlood smear for parasite clearance at 2 weeks
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Imizol

FAQs

Frequently asked questions

What is Imidocarb Dipropionate?
Imidocarb Dipropionate is a antiprotozoal (carbanilide derivative) used in pets. Binds to DNA minor groove and inhibits polyamine synthesis in protozoa, disrupting nucleic acid metabolism. Also concentrates in liver and kidney of protozoa, interfering with aerobic glycolysis. Active against Babesia, Hepatozoon, and Ehrlichia.
What is Imidocarb Dipropionate used for in pets?
Imidocarb Dipropionate is used in veterinary medicine for: Treatment of choice for Babesia canis (large Babesia); Off-label for feline babesiosis and cytauxzoonosis.
What is the Imidocarb Dipropionate dose for dogs?
For dogs, Imidocarb Dipropionate is typically dosed as follows — Treatment of choice for Babesia canis (large Babesia): 5–6 mg/kg IM/SQ Once or q14 days x 2–3 doses. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Imidocarb Dipropionate dose for cats?
For cats, Imidocarb Dipropionate is typically dosed as follows — Off-label for feline babesiosis and cytauxzoonosis: 3.5 mg/kg IM Once. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Imidocarb Dipropionate need a prescription?
Yes. Imidocarb Dipropionate is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

CDSCO approvals (India) — 2

Imidocarb Dipropionate Injection (Imizol)
M/s Intervet India pvt. Ltd., · Approved 21.01.2022
for the treatment and prevention of Babesiosis in cattle and horses. For the treatment of bovine anaplasmosis. For the t
Imidocarb Dipropionate Aqueous Injection 120 Mg/ml
M/s Intracin Pharmaceuticals Pvt. Ltd., · Approved 25.02.2022
For treatment of babesiosis in cattle sheep, horses and dogs and iof anaplasmosis in cattle. Treatemnt of ehrlichiosis i
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Antiprotozoal).

Atovaquone
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Selectively inhibits mitochondrial electron transport at complex III in protozoa, collapsing the mitochondrial membrane potential and blocking pyrimidine biosynthesis. Active against Babesia, Pneumocystis, Toxoplasma, and Hepatozoon.
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Diminazene
Rx
Aromatic diamidine compound that binds to kinetoplast DNA (kDNA) minor groove of trypanosomes and Babesia, disrupting DNA replication and transcription. Also inhibits aerobic glycolysis and delta-aminolevulinic acid synthetase in protozoa.
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