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Diminazene

Prescription
Antiprotozoal (Aromatic Diamidine)
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
1

Mechanism of action

Aromatic diamidine compound that binds to kinetoplast DNA (kDNA) minor groove of trypanosomes and Babesia, disrupting DNA replication and transcription. Also inhibits aerobic glycolysis and delta-aminolevulinic acid synthetase in protozoa.

At a glance

Class
Antiprotozoal (Aromatic Diamidine)
Schedule
Prescription
Storage
Store at room temperature; reconstituted solution use immediately

Dosing

🐕

Dog

Used for Babesia canis infection (large Babesia)
Dose
3.5–5 mg/kg
Route
IM (deep injection)
Frequency
Once; may repeat once in 24h
🐈

Cat

Very limited feline data
Dose
2 mg/kg
Route
IM
Frequency
Once
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature; reconstituted solution use immediately

Safety

Monitoring parameters

PCV and blood smear post-treatmentNeurological assessmentRenal and hepatic functionClinical response at 24–48h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Berenil
Ganaseg

FAQs

Frequently asked questions

What is Diminazene?
Diminazene is a antiprotozoal (aromatic diamidine) used in pets. Aromatic diamidine compound that binds to kinetoplast DNA (kDNA) minor groove of trypanosomes and Babesia, disrupting DNA replication and transcription. Also inhibits aerobic glycolysis and delta-aminolevulinic acid synthetase in protozoa.
What is Diminazene used for in pets?
Diminazene is used in veterinary medicine for: Used for Babesia canis infection (large Babesia); Very limited feline data.
What is the Diminazene dose for dogs?
For dogs, Diminazene is typically dosed as follows — Used for Babesia canis infection (large Babesia): 3.5–5 mg/kg IM (deep injection) Once; may repeat once in 24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Diminazene dose for cats?
For cats, Diminazene is typically dosed as follows — Very limited feline data: 2 mg/kg IM Once. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Diminazene need a prescription?
Yes. Diminazene is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

CDSCO approvals (India) — 1

Each ml contains: Diminazene Diaceturate 70 mg+ Phenazone BP 375 mg + chlorocres
M/s. Crescent Lab · Approved 13.02.2015
For the treatment of: Babesiosis caused by B.bovis, B.bigemina, B.motasi & B.canis. Trypanosomoisis caused by T.congolen
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Antiprotozoal).

Atovaquone
Rx
Selectively inhibits mitochondrial electron transport at complex III in protozoa, collapsing the mitochondrial membrane potential and blocking pyrimidine biosynthesis. Active against Babesia, Pneumocystis, Toxoplasma, and Hepatozoon.
dogcat
Imidocarb Dipropionate
Rx
Binds to DNA minor groove and inhibits polyamine synthesis in protozoa, disrupting nucleic acid metabolism. Also concentrates in liver and kidney of protozoa, interfering with aerobic glycolysis. Active against Babesia, Hepatozoon, and Ehrlichia.
dogcat
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