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Fluralaner

PrescriptionCDSCO approved
Isoxazoline ectoparasiticide
Last reviewed 19 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
5

Mechanism of action

Potently inhibits arthropod GABA-gated and glutamate-gated chloride channels, providing prolonged flea and tick protection lasting 12 weeks

At a glance

Class
Isoxazoline ectoparasiticide
Schedule
Prescription
Storage
Store below 30°C
CDSCO (India)
Vet-approved — 2015-01

Dosing

🐕

Dog

Flea and tick prevention/treatment
Dose
25–56 mg/kg
Route
PO
Frequency
Once every 12 weeks
Max dose
1400 mg
Duration: Year-round or seasonal
🐈

Cat

Flea and tick prevention/treatment
Dose
40–94 mg/kg
Route
Topical
Frequency
Once every 12 weeks
Max dose
500 mg
Duration: Year-round or seasonal
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Chewable tablet — 5

Strength
112.5mg (2–4.5kg)
Available in India
Strength
250mg (4.5–10kg)
Available in India
Strength
500mg (10–20kg)
Available in India
Strength
1000mg (20–40kg)
Available in India
Strength
1400mg (40–56kg)
Available in India

Storage

Store below 30°C

Safety

Use with caution

  • Dogs/cats with history of seizures
    Isoxazolines may lower seizure threshold
  • Puppies < 8 weeks or < 2 kg
    Safety not established

Adverse effects

Common
Vomiting
Decreased appetite
Diarrhoea
Lethargy
Serious
Seizures (rare)
Ataxia

Monitoring parameters

Ectoparasite burdenNeurological signs
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

International

Bravecto
MSD Animal Health

India

Bravecto
MSD India

FAQs

Frequently asked questions

What is Fluralaner?
Fluralaner is a isoxazoline ectoparasiticide used in pets. Potently inhibits arthropod GABA-gated and glutamate-gated chloride channels, providing prolonged flea and tick protection lasting 12 weeks
What is Fluralaner used for in pets?
Fluralaner is used in veterinary medicine for: Flea and tick prevention/treatment.
What is the Fluralaner dose for dogs?
For dogs, Fluralaner is typically dosed as follows — Flea and tick prevention/treatment: 25–56 mg/kg PO Once every 12 weeks. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Fluralaner dose for cats?
For cats, Fluralaner is typically dosed as follows — Flea and tick prevention/treatment: 40–94 mg/kg Topical Once every 12 weeks. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What are the side effects of Fluralaner?
Common: Vomiting, Decreased appetite, Diarrhoea, Lethargy. Serious (call your vet immediately): Seizures (rare), Ataxia.
Does Fluralaner need a prescription?
Yes. Fluralaner is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

CDSCO approvals (India) — 2

Fluralaner Chewable tablets 112.5mg/250mg/500mg/1000 mg/1400mg
M/s Intervet India Pvt Ltd · Approved 30-05.2017
For the treatment of tick and fliea infestations of dogs for 12 weeks.this veterinary medicinal product is a systemic in
Fluralaner and Moxidectin 112.5/5.6mg, 250/12.5mg, 500/25 mg spot-on solution
M/s Intervet India Pvt. Ltd. · Approved 02.08.2024
infestations by ticks and fleas, gastrointestinal nematodes (4th stage larvae, immature adults and adults of Toxocara ca
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Isoxazoline ectoparasiticide).

Afoxolaner
Rx
Inhibits GABA-gated and glutamate-gated chloride channels in arthropod neurons, causing uncontrolled neuromuscular activity and death of fleas and ticks
dog
Lotilaner
Rx
Selectively inhibits GABA-gated chloride channels and glutamate-gated chloride channels in arthropod nerve and muscle cells, causing uncontrolled neuromuscular activity and death of fleas and ticks. High selectivity for invertebrate vs. mammalian receptors.
dogcat
Sarolaner
Rx
Inhibits GABA-gated and glutamate-gated chloride channels in arthropod nervous systems, providing monthly flea and tick protection
dog
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