Potently inhibits arthropod GABA-gated and glutamate-gated chloride channels, providing prolonged flea and tick protection lasting 12 weeks
At a glance
Class
Isoxazoline ectoparasiticide
Dosing
Flea and tick prevention/treatment
Frequency
Once every 12 weeks
Duration: Year-round or seasonal
Flea and tick prevention/treatment
Frequency
Once every 12 weeks
Duration: Year-round or seasonal
Safety
Dogs/cats with history of seizures
Isoxazolines may lower seizure threshold
Puppies < 8 weeks or < 2 kg
Safety not established
Adverse effects
Common
Vomiting
Decreased appetite
Diarrhoea
Lethargy
Ectoparasite burdenNeurological signs
Interactions
No documented interactions.
Brands
International
Bravecto
MSD Animal Health
FAQs
Frequently asked questions
›What is Fluralaner?
Fluralaner is a isoxazoline ectoparasiticide used in pets. Potently inhibits arthropod GABA-gated and glutamate-gated chloride channels, providing prolonged flea and tick protection lasting 12 weeks
›What is Fluralaner used for in pets?
Fluralaner is used in veterinary medicine for: Flea and tick prevention/treatment.
›What is the Fluralaner dose for dogs?
For dogs, Fluralaner is typically dosed as follows — Flea and tick prevention/treatment: 25–56 mg/kg PO Once every 12 weeks. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Fluralaner dose for cats?
For cats, Fluralaner is typically dosed as follows — Flea and tick prevention/treatment: 40–94 mg/kg Topical Once every 12 weeks. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What are the side effects of Fluralaner?
Common: Vomiting, Decreased appetite, Diarrhoea, Lethargy. Serious (call your vet immediately): Seizures (rare), Ataxia.
›Does Fluralaner need a prescription?
Yes. Fluralaner is a prescription medication and should only be administered under veterinary supervision.
References
CDSCO approvals (India) — 2
Fluralaner Chewable tablets 112.5mg/250mg/500mg/1000 mg/1400mg
M/s Intervet India Pvt Ltd · Approved 30-05.2017
For the treatment of tick and fliea infestations of dogs for 12 weeks.this veterinary medicinal product is a systemic in
Fluralaner and Moxidectin 112.5/5.6mg, 250/12.5mg, 500/25 mg spot-on solution
M/s Intervet India Pvt. Ltd. · Approved 02.08.2024
infestations by ticks and fleas, gastrointestinal nematodes (4th stage larvae, immature adults and adults of Toxocara ca
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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