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Ceftiofur

PrescriptionCDSCO approved
Third-generation cephalosporin antibiotic
Last reviewed 19 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
3 available
Formulations
1

Mechanism of action

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins; broad-spectrum activity against gram-positive and gram-negative bacteria

At a glance

Class
Third-generation cephalosporin antibiotic
Schedule
Prescription
Storage
Refrigerate at 2–8°C; reconstituted solution stable for 7 days refrigerated
CDSCO (India)
Vet-approved — 1998-01

Dosing

🐕

Dog

Susceptible bacterial infections (skin, soft tissue, UTI)
Dose
2.2–4.4 mg/kg
Route
SC, IM
Frequency
SID
Max dose
200 mg
Duration: 5–14 days
🐈

Cat

Susceptible bacterial infections
Dose
2.2–4.4 mg/kg
Route
SC, IM
Frequency
SID
Max dose
50 mg
Duration: 5–14 days
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💉

Injectable suspension — 1

Strength
50mg/mL
Available in India

Storage

Refrigerate at 2–8°C; reconstituted solution stable for 7 days refrigerated

Safety

Absolute contraindications — do not use

  • Known hypersensitivity to cephalosporins or penicillins
    Cross-reactivity possible

Adverse effects

Common
Pain at injection site
Mild GI upset
Serious
Anaphylaxis
Blood dyscrasias

Monitoring parameters

CBC if prolonged useRenal function
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

International

Excede
Zoetis
Naxcel
Zoetis

India

Ceftizone
Intas

FAQs

Frequently asked questions

What is Ceftiofur?
Ceftiofur is a third-generation cephalosporin antibiotic used in pets. Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins; broad-spectrum activity against gram-positive and gram-negative bacteria
What is Ceftiofur used for in pets?
Ceftiofur is used in veterinary medicine for: Susceptible bacterial infections (skin, soft tissue, UTI); Susceptible bacterial infections.
What is the Ceftiofur dose for dogs?
For dogs, Ceftiofur is typically dosed as follows — Susceptible bacterial infections (skin, soft tissue, UTI): 2.2–4.4 mg/kg SC/IM SID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Ceftiofur dose for cats?
For cats, Ceftiofur is typically dosed as follows — Susceptible bacterial infections: 2.2–4.4 mg/kg SC/IM SID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What are the side effects of Ceftiofur?
Common: Pain at injection site, Mild GI upset. Serious (call your vet immediately): Anaphylaxis, Blood dyscrasias.
Does Ceftiofur need a prescription?
Yes. Ceftiofur is a prescription medication and should only be administered under veterinary supervision.
When should Ceftiofur not be used?
Do not use Ceftiofur if: Known hypersensitivity to cephalosporins or penicillins.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Third-generation cephalosporin antibiotic).

Cefpodoxime Proxetil
Rx
Inhibits bacterial cell wall synthesis; broader gram-negative spectrum than first-generation cephalosporins
dogcat
Ceftriaxone
Rx
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBP), providing broad-spectrum bactericidal activity against gram-positive and gram-negative organisms
dogcat
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