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Vecuronium

Prescription
Non-Depolarizing Neuromuscular Blocking Agent
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Interactions
1 documented
Formulations
1

Mechanism of action

Aminosteroid non-depolarizing NMBA that competitively blocks nicotinic receptors at the neuromuscular junction. Intermediate duration (20–40 min). No histamine release (unlike atracurium). Primarily hepatic elimination.

At a glance

Class
Non-Depolarizing Neuromuscular Blocking Agent
Schedule
Prescription
Storage
Refrigerate powder 2–8°C; reconstituted stable 24h at room temperature or 48h refrigerated

Dosing

🐕

Dog

Used for intraoperative muscle relaxation
Dose
0.05–0.1 mg/kg
Route
IV
Frequency
q15–25 min
🐈

Cat

Lower doses in cats
Dose
0.025–0.05 mg/kg
Route
IV
Frequency
q20–30 min
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Refrigerate powder 2–8°C; reconstituted stable 24h at room temperature or 48h refrigerated

Safety

Monitoring parameters

TOF monitoringSpO2 and ETCO2Adequate reversal before extubationVentilation (mandatory)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

Moderate — 1

Gentamicin (Systemic)
moderate
Same aminoglycoside potentiation of non-depolarizing NMB as with rocuronium.
Management: Reduce NMBA dose. Monitor TOF. Ensure full reversal before extubation.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Brands

Other markets

Norcuron

FAQs

Frequently asked questions

What is Vecuronium?
Vecuronium is a non-depolarizing neuromuscular blocking agent used in pets. Aminosteroid non-depolarizing NMBA that competitively blocks nicotinic receptors at the neuromuscular junction. Intermediate duration (20–40 min). No histamine release (unlike atracurium). Primarily hepatic elimination.
What is Vecuronium used for in pets?
Vecuronium is used in veterinary medicine for: Used for intraoperative muscle relaxation; Lower doses in cats.
What is the Vecuronium dose for dogs?
For dogs, Vecuronium is typically dosed as follows — Used for intraoperative muscle relaxation: 0.05–0.1 mg/kg IV q15–25 min. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Vecuronium dose for cats?
For cats, Vecuronium is typically dosed as follows — Lower doses in cats: 0.025–0.05 mg/kg IV q20–30 min. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Vecuronium need a prescription?
Yes. Vecuronium is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Non-Depolarizing Neuromuscular Blocking Agent).

Atracurium
Rx
Competitive antagonist at nicotinic acetylcholine receptors at the neuromuscular junction, preventing muscle depolarization and causing skeletal muscle paralysis. Undergoes Hofmann elimination — organ-independent metabolism.
dogcat
Rocuronium
Rx
Aminosteroid non-depolarizing NMBA that competitively blocks nicotinic acetylcholine receptors at the neuromuscular junction. Fastest onset of non-depolarizing agents (1–2 min). Can be fully reversed by sugammadex (gamma-cyclodextrin — encapsulation reversal).
dogcat
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