Bactericidal aminoglycoside binding 30S ribosomal subunit. Excellent gram-negative spectrum including Pseudomonas. Better anti-Pseudomonal activity than gentamicin ophthalmic. TobraDex combination adds anti-inflammatory dexamethasone.
At a glance
Class
Ophthalmic Aminoglycoside Antibiotic
Storage
Store at room temperature; TobraDex suspension — shake well
Dosing
Used for bacterial conjunctivitis and keratitis
Safety
Clinical responseIOP (TobraDex)Corneal fluorescein stain before TobraDex use
Interactions
No documented interactions.
Brands
Other markets
TobraDex (with dexamethasone)
FAQs
Frequently asked questions
›What is Tobramycin Ophthalmic?
Tobramycin Ophthalmic is a ophthalmic aminoglycoside antibiotic used in pets. Bactericidal aminoglycoside binding 30S ribosomal subunit. Excellent gram-negative spectrum including Pseudomonas. Better anti-Pseudomonal activity than gentamicin ophthalmic. TobraDex combination adds anti-inflammatory dexamethasone.
›What is Tobramycin Ophthalmic used for in pets?
Tobramycin Ophthalmic is used in veterinary medicine for: Used for bacterial conjunctivitis and keratitis; Same as dogs.
›What is the Tobramycin Ophthalmic dose for dogs?
For dogs, Tobramycin Ophthalmic is typically dosed as follows — Used for bacterial conjunctivitis and keratitis: undefined undefined Ophthalmic q1–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Tobramycin Ophthalmic dose for cats?
For cats, Tobramycin Ophthalmic is typically dosed as follows — Same as dogs: undefined undefined Ophthalmic q4–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Tobramycin Ophthalmic need a prescription?
Yes. Tobramycin Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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