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Tobramycin Ophthalmic

Prescription
Ophthalmic Aminoglycoside Antibiotic
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
3

Mechanism of action

Bactericidal aminoglycoside binding 30S ribosomal subunit. Excellent gram-negative spectrum including Pseudomonas. Better anti-Pseudomonal activity than gentamicin ophthalmic. TobraDex combination adds anti-inflammatory dexamethasone.

At a glance

Class
Ophthalmic Aminoglycoside Antibiotic
Schedule
Prescription
Storage
Store at room temperature; TobraDex suspension — shake well

Dosing

🐕

Dog

Used for bacterial conjunctivitis and keratitis
Dose
Route
Ophthalmic
Frequency
q1–6h
🐈

Cat

Same as dogs
Dose
Route
Ophthalmic
Frequency
q4–6h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 3

Strength
Strength
Strength

Storage

Store at room temperature; TobraDex suspension — shake well

Safety

Monitoring parameters

Clinical responseIOP (TobraDex)Corneal fluorescein stain before TobraDex use
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Tobrex
Novartis/Alcon
TobraDex (with dexamethasone)

FAQs

Frequently asked questions

What is Tobramycin Ophthalmic?
Tobramycin Ophthalmic is a ophthalmic aminoglycoside antibiotic used in pets. Bactericidal aminoglycoside binding 30S ribosomal subunit. Excellent gram-negative spectrum including Pseudomonas. Better anti-Pseudomonal activity than gentamicin ophthalmic. TobraDex combination adds anti-inflammatory dexamethasone.
What is Tobramycin Ophthalmic used for in pets?
Tobramycin Ophthalmic is used in veterinary medicine for: Used for bacterial conjunctivitis and keratitis; Same as dogs.
What is the Tobramycin Ophthalmic dose for dogs?
For dogs, Tobramycin Ophthalmic is typically dosed as follows — Used for bacterial conjunctivitis and keratitis: undefined undefined Ophthalmic q1–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Tobramycin Ophthalmic dose for cats?
For cats, Tobramycin Ophthalmic is typically dosed as follows — Same as dogs: undefined undefined Ophthalmic q4–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Tobramycin Ophthalmic need a prescription?
Yes. Tobramycin Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Ophthalmic Aminoglycoside Antibiotic).

Gentamicin Ophthalmic
Rx
Bactericidal aminoglycoside that binds 30S ribosomal subunit. Concentration-dependent killing with significant post-antibiotic effect. Excellent gram-negative activity including Pseudomonas. No systemic nephro/ototoxicity from topical use.
dogcat
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