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Gentamicin Ophthalmic

Prescription
Ophthalmic Aminoglycoside Antibiotic
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
3

Mechanism of action

Bactericidal aminoglycoside that binds 30S ribosomal subunit. Concentration-dependent killing with significant post-antibiotic effect. Excellent gram-negative activity including Pseudomonas. No systemic nephro/ototoxicity from topical use.

At a glance

Class
Ophthalmic Aminoglycoside Antibiotic
Schedule
Prescription
Storage
Store at room temperature; fortified solution refrigerated, use within 7–14 days

Dosing

🐕

Dog

Used for bacterial conjunctivitis, corneal ulcers (especially Pseudomonas — fort
Dose
Route
Ophthalmic
Frequency
q1–8h depending on severity
🐈

Cat

Same as dogs
Dose
Route
Ophthalmic
Frequency
q4–6h

Formulations

💊

Other — 3

Strength
Strength
Strength

Storage

Store at room temperature; fortified solution refrigerated, use within 7–14 days

Safety

Monitoring parameters

Clinical responseCulture and sensitivity for refractory casesCorneal epithelial health (prolonged use)

Interactions

No documented interactions.

Brands

Other markets

Gentak
Gentocin Ophthalmic

FAQs

Frequently asked questions

What is Gentamicin Ophthalmic?
Gentamicin Ophthalmic is a ophthalmic aminoglycoside antibiotic used in pets. Bactericidal aminoglycoside that binds 30S ribosomal subunit. Concentration-dependent killing with significant post-antibiotic effect. Excellent gram-negative activity including Pseudomonas. No systemic nephro/ototoxicity from topical use.
What is Gentamicin Ophthalmic used for in pets?
Gentamicin Ophthalmic is used in veterinary medicine for: Used for bacterial conjunctivitis, corneal ulcers (especially Pseudomonas — fort; Same as dogs.
What is the Gentamicin Ophthalmic dose for dogs?
For dogs, Gentamicin Ophthalmic is typically dosed as follows — Used for bacterial conjunctivitis, corneal ulcers (especially Pseudomonas — fort: undefined undefined Ophthalmic q1–8h depending on severity. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Gentamicin Ophthalmic dose for cats?
For cats, Gentamicin Ophthalmic is typically dosed as follows — Same as dogs: undefined undefined Ophthalmic q4–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Gentamicin Ophthalmic need a prescription?
Yes. Gentamicin Ophthalmic is a prescription medication and should only be administered under veterinary supervision.

References

References

Textbooks & handbooks

  • Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
  • Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
  • Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
  • National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
  • The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/

Clinical guidelines & consensus

  • Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
  • American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.

Journals & peer-reviewed studies

  • Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
  • Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
  • ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control

Regulatory & approvals

  • Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/

Databases

  • Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Related medicines

Other medicines in the same class (Ophthalmic Aminoglycoside Antibiotic).

Tobramycin Ophthalmic
Rx
Bactericidal aminoglycoside binding 30S ribosomal subunit. Excellent gram-negative spectrum including Pseudomonas. Better anti-Pseudomonal activity than gentamicin ophthalmic. TobraDex combination adds anti-inflammatory dexamethasone.
dogcat