Irreversibly inhibits H+/K+-ATPase (proton pump) in gastric parietal cells, blocking the final step of gastric acid secretion. Effective regardless of stimulation pathway. More rapid onset than other PPIs.
At a glance
Class
Proton Pump Inhibitor (PPI)
Storage
Store at room temperature below 25°C, protect from moisture and light
Dosing
Acid suppression for gastric ulceration, esophagitis, GERD, and Helicobacter tre
Used for esophagitis, gastric ulceration, and hyperacidity
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Clinical response (GI symptom resolution)Electrolytes with prolonged useEndoscopy for refractory cases
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Rabeprazole?
Rabeprazole is a proton pump inhibitor (ppi) used in pets. Irreversibly inhibits H+/K+-ATPase (proton pump) in gastric parietal cells, blocking the final step of gastric acid secretion. Effective regardless of stimulation pathway. More rapid onset than other PPIs.
›What is Rabeprazole used for in pets?
Rabeprazole is used in veterinary medicine for: Acid suppression for gastric ulceration, esophagitis, GERD, and Helicobacter tre; Used for esophagitis, gastric ulceration, and hyperacidity.
›What is the Rabeprazole dose for dogs?
For dogs, Rabeprazole is typically dosed as follows — Acid suppression for gastric ulceration, esophagitis, GERD, and Helicobacter tre: 1–2 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Rabeprazole dose for cats?
For cats, Rabeprazole is typically dosed as follows — Used for esophagitis, gastric ulceration, and hyperacidity: 1–2 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Rabeprazole need a prescription?
Yes. Rabeprazole is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database