Synthetic progestogen that binds progesterone receptors, suppressing gonadotropin release (LH and FSH) and inhibiting estrus. Also has anti-inflammatory and immunomodulatory properties. Long-acting depot formulation provides sustained progestogenic effect.
At a glance
Class
Synthetic Progestogen
Storage
Store at room temperature; shake injectable suspension well before use
Dosing
Used for estrus suppression, testosterone-responsive conditions, and some dermat
Frequency
Variable — see notes
Used for eosinophilic granuloma complex, miliary dermatitis, and estrus suppress
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Blood glucoseUterine health (ultrasound)Mammary gland examinationBody weightAdrenal function
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Medroxyprogesterone Acetate?
Medroxyprogesterone Acetate is a synthetic progestogen used in pets. Synthetic progestogen that binds progesterone receptors, suppressing gonadotropin release (LH and FSH) and inhibiting estrus. Also has anti-inflammatory and immunomodulatory properties. Long-acting depot formulation provides sustained progestogenic effect.
›What is Medroxyprogesterone Acetate used for in pets?
Medroxyprogesterone Acetate is used in veterinary medicine for: Used for estrus suppression, testosterone-responsive conditions, and some dermat; Used for eosinophilic granuloma complex, miliary dermatitis, and estrus suppress.
›What is the Medroxyprogesterone Acetate dose for dogs?
For dogs, Medroxyprogesterone Acetate is typically dosed as follows — Used for estrus suppression, testosterone-responsive conditions, and some dermat: 2–5 mg/kg IM/SQ/PO Variable — see notes. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Medroxyprogesterone Acetate dose for cats?
For cats, Medroxyprogesterone Acetate is typically dosed as follows — Used for eosinophilic granuloma complex, miliary dermatitis, and estrus suppress: 2.5–5 mg/kg IM/SQ/PO Variable. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Medroxyprogesterone Acetate need a prescription?
Yes. Medroxyprogesterone Acetate is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database