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Altrenogest

Prescription
Synthetic Progestogen
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

Potent synthetic progestogen (norethisterone derivative) that mimics progesterone by binding to progesterone receptors, suppressing LH release, preventing ovulation, and maintaining pregnancy in progestogen-dependent species.

At a glance

Class
Synthetic Progestogen
Schedule
Prescription
Storage
Store at room temperature; use extreme caution (human hazard — skin absorption); gloves mandatory

Dosing

🐕

Dog

Rarely used in dogs
Dose
Route
PO
Frequency
q24h
🐈

Cat

Not a routine feline drug
Dose
Route
PO
Frequency
N/A

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature; use extreme caution (human hazard — skin absorption); gloves mandatory

Safety

Monitoring parameters

Progesterone levelsUterine health (ultrasound)Blood glucose with long-term use

Interactions

No documented interactions.

Brands

Other markets

Regu-Mate
Matrix

FAQs

Frequently asked questions

What is Altrenogest?
Altrenogest is a synthetic progestogen used in pets. Potent synthetic progestogen (norethisterone derivative) that mimics progesterone by binding to progesterone receptors, suppressing LH release, preventing ovulation, and maintaining pregnancy in progestogen-dependent species.
What is Altrenogest used for in pets?
Altrenogest is used in veterinary medicine for: Rarely used in dogs; Not a routine feline drug.
What is the Altrenogest dose for dogs?
For dogs, Altrenogest is typically dosed as follows — Rarely used in dogs: undefined undefined PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Altrenogest dose for cats?
For cats, Altrenogest is typically dosed as follows — Not a routine feline drug: undefined undefined PO N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Altrenogest need a prescription?
Yes. Altrenogest is a prescription medication and should only be administered under veterinary supervision.

References

CDSCO approvals (India) — 1

Altrenogest 2.2 mg/ml oral solution for horses
M/s Intervet India pvt ltd., · Approved 30.11.2021
In mares with significant follicular activity during the transitional period between seasonal anoestrus and the breeding
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)

References

Textbooks & handbooks

  • Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
  • Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
  • Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
  • National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
  • The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/

Clinical guidelines & consensus

  • Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
  • American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.

Journals & peer-reviewed studies

  • Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
  • Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
  • ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control

Regulatory & approvals

  • Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/

Databases

  • Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Related medicines

Other medicines in the same class (Synthetic Progestogen).

Medroxyprogesterone Acetate
Rx
Synthetic progestogen that binds progesterone receptors, suppressing gonadotropin release (LH and FSH) and inhibiting estrus. Also has anti-inflammatory and immunomodulatory properties. Long-acting depot formulation provides sustained progestogenic effect.
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