Activates PPARα, increasing lipoprotein lipase activity and reducing hepatic VLDL production. Primarily lowers triglycerides (40–60%) with modest LDL reduction and HDL increase. Older fibrate — fenofibrate generally preferred.
At a glance
Class
Fibric Acid Derivative (Lipid-Lowering)
Storage
Store at room temperature below 25°C
Dosing
Used for severe hypertriglyceridemia in Miniature Schnauzers and other breeds
Feline hyperlipidemia is uncommon
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Fasting lipid panel at 4–6 weeksHepatic enzymesCK (myopathy)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Gemfibrozil?
Gemfibrozil is a fibric acid derivative (lipid-lowering) used in pets. Activates PPARα, increasing lipoprotein lipase activity and reducing hepatic VLDL production. Primarily lowers triglycerides (40–60%) with modest LDL reduction and HDL increase. Older fibrate — fenofibrate generally preferred.
›What is Gemfibrozil used for in pets?
Gemfibrozil is used in veterinary medicine for: Used for severe hypertriglyceridemia in Miniature Schnauzers and other breeds; Feline hyperlipidemia is uncommon.
›What is the Gemfibrozil dose for dogs?
For dogs, Gemfibrozil is typically dosed as follows — Used for severe hypertriglyceridemia in Miniature Schnauzers and other breeds: undefined undefined PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Gemfibrozil dose for cats?
For cats, Gemfibrozil is typically dosed as follows — Feline hyperlipidemia is uncommon: undefined undefined N/A N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Gemfibrozil need a prescription?
Yes. Gemfibrozil is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database