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Flurbiprofen (Ophthalmic)

Prescription
Ophthalmic NSAID
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
1

Mechanism of action

Topical ophthalmic NSAID that inhibits COX-1 and COX-2, reducing prostaglandin synthesis in ocular tissues. Used to reduce intraoperative miosis and treat ocular inflammation.

At a glance

Class
Ophthalmic NSAID
Schedule
Prescription
Storage
Store at room temperature; discard 28 days after opening

Dosing

🐕

Dog

Used peri-operatively for cataract surgery to prevent intraoperative miosis
Dose
Route
Ophthalmic
Frequency
q6–8h (maintenance)
🐈

Cat

Monitor for corneal ulceration; avoid in eyes with compromised epithelium
Dose
Route
Ophthalmic
Frequency
q6–8h

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature; discard 28 days after opening

Safety

Monitoring parameters

Corneal integrity (fluorescein staining)Intraocular pressureSigns of infection

Interactions

No documented interactions.

Brands

Other markets

Ocufen
Flurofen

FAQs

Frequently asked questions

What is Flurbiprofen (Ophthalmic)?
Flurbiprofen (Ophthalmic) is a ophthalmic nsaid used in pets. Topical ophthalmic NSAID that inhibits COX-1 and COX-2, reducing prostaglandin synthesis in ocular tissues. Used to reduce intraoperative miosis and treat ocular inflammation.
What is Flurbiprofen (Ophthalmic) used for in pets?
Flurbiprofen (Ophthalmic) is used in veterinary medicine for: Used peri-operatively for cataract surgery to prevent intraoperative miosis; Monitor for corneal ulceration; avoid in eyes with compromised epithelium.
What is the Flurbiprofen (Ophthalmic) dose for dogs?
For dogs, Flurbiprofen (Ophthalmic) is typically dosed as follows — Used peri-operatively for cataract surgery to prevent intraoperative miosis: undefined undefined Ophthalmic q6–8h (maintenance). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Flurbiprofen (Ophthalmic) dose for cats?
For cats, Flurbiprofen (Ophthalmic) is typically dosed as follows — Monitor for corneal ulceration; avoid in eyes with compromised epithelium: undefined undefined Ophthalmic q6–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Flurbiprofen (Ophthalmic) need a prescription?
Yes. Flurbiprofen (Ophthalmic) is a prescription medication and should only be administered under veterinary supervision.

References

References

Textbooks & handbooks

  • Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
  • Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
  • Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
  • National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
  • The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/

Clinical guidelines & consensus

  • Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
  • American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.

Journals & peer-reviewed studies

  • Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
  • Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
  • ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control

Regulatory & approvals

  • Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/

Databases

  • Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Related medicines

Other medicines in the same class (Ophthalmic NSAID).

Diclofenac Ophthalmic
Rx
Topical non-selective COX inhibitor that reduces prostaglandin synthesis in ocular tissues. Prevents intraoperative miosis and treats post-surgical inflammation and pain. Does not raise IOP like corticosteroids.
dogcat
Nepafenac Ophthalmic
Rx
Prodrug that penetrates the cornea intact and is converted to active amfenac by intraocular hydrolases. Amfenac inhibits COX-1 and COX-2 within the eye. Prodrug design provides better corneal penetration and less surface toxicity than other ophthalmic NSAIDs.
dogcat