Competitive H1-receptor antagonist that blocks histamine-mediated vasodilation, increased vascular permeability, and pruritus. Moderate anticholinergic and sedative properties.
At a glance
Class
First-Generation Antihistamine (H1 Blocker)
Storage
Store at room temperature, protect from moisture
Dosing
Used for allergic dermatitis, urticaria, and pruritus
Used for feline allergic skin disease
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Pruritus responseSedation level
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Clemastine?
Clemastine is a first-generation antihistamine (h1 blocker) used in pets. Competitive H1-receptor antagonist that blocks histamine-mediated vasodilation, increased vascular permeability, and pruritus. Moderate anticholinergic and sedative properties.
›What is Clemastine used for in pets?
Clemastine is used in veterinary medicine for: Used for allergic dermatitis, urticaria, and pruritus; Used for feline allergic skin disease.
›What is the Clemastine dose for dogs?
For dogs, Clemastine is typically dosed as follows — Used for allergic dermatitis, urticaria, and pruritus: 0.05–0.1 mg/kg PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Clemastine dose for cats?
For cats, Clemastine is typically dosed as follows — Used for feline allergic skin disease: 0.34–0.68 mg/cat PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Clemastine need a prescription?
Clemastine is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database