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Cefaclor

Prescription
Second-Generation Cephalosporin
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

Bactericidal beta-lactam that inhibits cell wall synthesis. Second-generation spectrum bridges gram-positive (first-gen) and gram-negative (third-gen) coverage. More active against H. influenzae and Moraxella than first-generation cephalosporins.

At a glance

Class
Second-Generation Cephalosporin
Schedule
Prescription
Storage
Capsules at room temperature; suspension refrigerated, use within 14 days

Dosing

🐕

Dog

Used for skin, soft tissue, respiratory, and urinary tract infections
Dose
4–20 mg/kg
Route
PO
Frequency
q8h
🐈

Cat

Limited feline data
Dose
10–15 mg/kg
Route
PO
Frequency
q8h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Capsules at room temperature; suspension refrigerated, use within 14 days

Safety

Monitoring parameters

Clinical response at 3–5 daysCulture and sensitivity
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Ceclor
Raniclor

FAQs

Frequently asked questions

What is Cefaclor?
Cefaclor is a second-generation cephalosporin used in pets. Bactericidal beta-lactam that inhibits cell wall synthesis. Second-generation spectrum bridges gram-positive (first-gen) and gram-negative (third-gen) coverage. More active against H. influenzae and Moraxella than first-generation cephalosporins.
What is Cefaclor used for in pets?
Cefaclor is used in veterinary medicine for: Used for skin, soft tissue, respiratory, and urinary tract infections; Limited feline data.
What is the Cefaclor dose for dogs?
For dogs, Cefaclor is typically dosed as follows — Used for skin, soft tissue, respiratory, and urinary tract infections: 4–20 mg/kg PO q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Cefaclor dose for cats?
For cats, Cefaclor is typically dosed as follows — Limited feline data: 10–15 mg/kg PO q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Cefaclor need a prescription?
Yes. Cefaclor is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Second-Generation Cephalosporin).

Cefotetan
Rx
Cephamycin antibiotic with enhanced anaerobic coverage compared to other second-gen cephalosporins due to 7-alpha-methoxy group. Excellent activity against Bacteroides fragilis and most Enterobacteriaceae.
dogcat
Cefuroxime
Rx
Beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Bactericidal with activity against both gram-positive and gram-negative organisms.
dogcat
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