Bactericidal beta-lactam that inhibits cell wall synthesis. Second-generation spectrum bridges gram-positive (first-gen) and gram-negative (third-gen) coverage. More active against H. influenzae and Moraxella than first-generation cephalosporins.
At a glance
Class
Second-Generation Cephalosporin
Storage
Capsules at room temperature; suspension refrigerated, use within 14 days
Dosing
Used for skin, soft tissue, respiratory, and urinary tract infections
Safety
Clinical response at 3–5 daysCulture and sensitivity
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Cefaclor?
Cefaclor is a second-generation cephalosporin used in pets. Bactericidal beta-lactam that inhibits cell wall synthesis. Second-generation spectrum bridges gram-positive (first-gen) and gram-negative (third-gen) coverage. More active against H. influenzae and Moraxella than first-generation cephalosporins.
›What is Cefaclor used for in pets?
Cefaclor is used in veterinary medicine for: Used for skin, soft tissue, respiratory, and urinary tract infections; Limited feline data.
›What is the Cefaclor dose for dogs?
For dogs, Cefaclor is typically dosed as follows — Used for skin, soft tissue, respiratory, and urinary tract infections: 4–20 mg/kg PO q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Cefaclor dose for cats?
For cats, Cefaclor is typically dosed as follows — Limited feline data: 10–15 mg/kg PO q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Cefaclor need a prescription?
Yes. Cefaclor is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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