Cephamycin antibiotic with enhanced anaerobic coverage compared to other second-gen cephalosporins due to 7-alpha-methoxy group. Excellent activity against Bacteroides fragilis and most Enterobacteriaceae.
At a glance
Class
Second-Generation Cephalosporin (Cephamycin)
Storage
Powder at room temperature; reconstituted stable 24h at room temperature or 96h refrigerated
Dosing
Used for mixed aerobic-anaerobic infections (peritonitis, pyometra, aspiration p
Used for intra-abdominal infections and pyometra in cats
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Coagulation (PT) with prolonged useCBCClinical response
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Cefotetan?
Cefotetan is a second-generation cephalosporin (cephamycin) used in pets. Cephamycin antibiotic with enhanced anaerobic coverage compared to other second-gen cephalosporins due to 7-alpha-methoxy group. Excellent activity against Bacteroides fragilis and most Enterobacteriaceae.
›What is Cefotetan used for in pets?
Cefotetan is used in veterinary medicine for: Used for mixed aerobic-anaerobic infections (peritonitis, pyometra, aspiration p; Used for intra-abdominal infections and pyometra in cats.
›What is the Cefotetan dose for dogs?
For dogs, Cefotetan is typically dosed as follows — Used for mixed aerobic-anaerobic infections (peritonitis, pyometra, aspiration p: 30 mg/kg IV/SQ q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Cefotetan dose for cats?
For cats, Cefotetan is typically dosed as follows — Used for intra-abdominal infections and pyometra in cats: 30 mg/kg IV q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Cefotetan need a prescription?
Yes. Cefotetan is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database