Glycopeptide antibiotic that generates reactive oxygen species causing single- and double-strand DNA breaks. Cell-cycle specific (G2 and M phase). Inactivated by bleomycin hydrolase — low in lung and skin (highest toxicity there).
At a glance
Class
Antitumor Antibiotic (Chemotherapy)
Schedule
Prescription (Chemotherapy)
Storage
Refrigerate 2–8°C; reconstituted solution stable 24h at room temperature; chemotherapy precautions
Dosing
Used for squamous cell carcinoma, fibrosarcoma
Used for squamous cell carcinoma and injection-site sarcomas
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Chest radiographs before each cycle (pulmonary fibrosis)Renal function (BUN, creatinine)Cumulative dose tracking
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Bleomycin?
Bleomycin is a antitumor antibiotic (chemotherapy) used in pets. Glycopeptide antibiotic that generates reactive oxygen species causing single- and double-strand DNA breaks. Cell-cycle specific (G2 and M phase). Inactivated by bleomycin hydrolase — low in lung and skin (highest toxicity there).
›What is Bleomycin used for in pets?
Bleomycin is used in veterinary medicine for: Used for squamous cell carcinoma, fibrosarcoma; Used for squamous cell carcinoma and injection-site sarcomas.
›What is the Bleomycin dose for dogs?
For dogs, Bleomycin is typically dosed as follows — Used for squamous cell carcinoma, fibrosarcoma: undefined undefined IV/SQ Weekly. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Bleomycin dose for cats?
For cats, Bleomycin is typically dosed as follows — Used for squamous cell carcinoma and injection-site sarcomas: undefined undefined IV/SQ Weekly. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Bleomycin need a prescription?
Yes. Bleomycin is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database