Second-generation triazole that inhibits fungal 14α-demethylase, blocking ergosterol synthesis. Broadest antifungal spectrum of topical ophthalmic azoles including Aspergillus, Fusarium, Candida, and many molds. Excellent corneal penetration.
At a glance
Class
Ophthalmic Triazole Antifungal
Storage
Refrigerate compounded solution; stable 30 days refrigerated; protect from light
Dosing
Drug of choice for fungal keratitis (Aspergillus, Fusarium)
Frequency
q1–6h (frequency depends on severity)
Fungal keratitis uncommon in cats but occurs post-trauma
Safety
Corneal lesion response (slit lamp)Fungal cultureCorneal thickness (stromal melting)Treat 2–4 weeks beyond clinical resolution
Interactions
No documented interactions.
Brands
Other markets
Voriconazole Ophthalmic (compounded)
FAQs
Frequently asked questions
›What is Voriconazole Ophthalmic?
Voriconazole Ophthalmic is a ophthalmic triazole antifungal used in pets. Second-generation triazole that inhibits fungal 14α-demethylase, blocking ergosterol synthesis. Broadest antifungal spectrum of topical ophthalmic azoles including Aspergillus, Fusarium, Candida, and many molds. Excellent corneal penetration.
›What is Voriconazole Ophthalmic used for in pets?
Voriconazole Ophthalmic is used in veterinary medicine for: Drug of choice for fungal keratitis (Aspergillus, Fusarium); Fungal keratitis uncommon in cats but occurs post-trauma.
›What is the Voriconazole Ophthalmic dose for dogs?
For dogs, Voriconazole Ophthalmic is typically dosed as follows — Drug of choice for fungal keratitis (Aspergillus, Fusarium): undefined undefined Ophthalmic q1–6h (frequency depends on severity). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Voriconazole Ophthalmic dose for cats?
For cats, Voriconazole Ophthalmic is typically dosed as follows — Fungal keratitis uncommon in cats but occurs post-trauma: undefined undefined Ophthalmic q4–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Voriconazole Ophthalmic need a prescription?
Yes. Voriconazole Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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