Semi-synthetic derivative of vinblastine that binds tubulin and inhibits microtubule assembly, arresting cells in metaphase. Greater selectivity for mitotic microtubules (less neurotoxicity than vincristine). Active against carcinomas and lymphomas.
At a glance
Class
Semi-Synthetic Vinca Alkaloid (Chemotherapy)
Schedule
Prescription (Chemotherapy)
Storage
Refrigerate 2–8°C; protect from light; chemotherapy precautions
Dosing
Used for pulmonary carcinoma, mammary carcinoma, and transitional cell carcinoma
Frequency
Weekly or q2 weeks per protocol
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
CBC at nadir and before each dose (ANC ≥1500 to proceed)Catheter patencyHepatic functionTumor response
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Vinorelbine?
Vinorelbine is a semi-synthetic vinca alkaloid (chemotherapy) used in pets. Semi-synthetic derivative of vinblastine that binds tubulin and inhibits microtubule assembly, arresting cells in metaphase. Greater selectivity for mitotic microtubules (less neurotoxicity than vincristine). Active against carcinomas and lymphomas.
›What is Vinorelbine used for in pets?
Vinorelbine is used in veterinary medicine for: Used for pulmonary carcinoma, mammary carcinoma, and transitional cell carcinoma; Very limited feline data.
›What is the Vinorelbine dose for dogs?
For dogs, Vinorelbine is typically dosed as follows — Used for pulmonary carcinoma, mammary carcinoma, and transitional cell carcinoma: 15–18 mg/m² IV (vesicant) Weekly or q2 weeks per protocol. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Vinorelbine dose for cats?
For cats, Vinorelbine is typically dosed as follows — Very limited feline data: undefined undefined IV Per protocol. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Vinorelbine need a prescription?
Yes. Vinorelbine is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database