Inhibits mitochondrial electron transport and pyrimidine biosynthesis in all intracellular stages of coccidia (schizonts, gamonts, and oocysts). Coccidiocidal — kills all life cycle stages rather than just inhibiting reproduction. Single-dose treatment effective.
At a glance
Class
Triazinone Anticoccidial
Storage
Store at room temperature below 25°C, protect from light
Dosing
Used for Cystoisospora (Isospora) coccidiosis in puppies
Frequency
Once (repeat in 7–10 days if needed)
Effective for feline coccidiosis
Frequency
Once (repeat in 7–10 days)
Safety
Fecal oocyst count 7–14 days post-treatmentClinical improvement (diarrhea resolution)
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Toltrazuril?
Toltrazuril is a triazinone anticoccidial used in pets. Inhibits mitochondrial electron transport and pyrimidine biosynthesis in all intracellular stages of coccidia (schizonts, gamonts, and oocysts). Coccidiocidal — kills all life cycle stages rather than just inhibiting reproduction. Single-dose treatment effective.
›What is Toltrazuril used for in pets?
Toltrazuril is used in veterinary medicine for: Used for Cystoisospora (Isospora) coccidiosis in puppies; Effective for feline coccidiosis.
›What is the Toltrazuril dose for dogs?
For dogs, Toltrazuril is typically dosed as follows — Used for Cystoisospora (Isospora) coccidiosis in puppies: 10–30 mg/kg PO Once (repeat in 7–10 days if needed). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Toltrazuril dose for cats?
For cats, Toltrazuril is typically dosed as follows — Effective for feline coccidiosis: 10–30 mg/kg PO Once (repeat in 7–10 days). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Toltrazuril need a prescription?
Yes. Toltrazuril is a prescription medication and should only be administered under veterinary supervision.
References
CDSCO approvals (India) — 2
Toltrazuril Solution
M/s Bayer · Approved 30.04.1998
Toltrazuril 2.5% solution
M/s Bayer India Limited · Approved 08.06.2001
for treatment of coccoidiasis in poultry
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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