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Timolol Ophthalmic

Prescription
Ophthalmic Non-Selective Beta-Blocker
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

Non-selective beta-1/beta-2 adrenergic antagonist that reduces aqueous humor production by the ciliary body (beta-2 receptor blockade decreases cAMP-mediated aqueous secretion). Lowers IOP ~20–25% without affecting pupil size or accommodation.

At a glance

Class
Ophthalmic Non-Selective Beta-Blocker
Schedule
Prescription
Storage
Store at room temperature, protect from light

Dosing

🐕

Dog

Used for chronic glaucoma — often combined with dorzolamide (Cosopt = dorzolamid
Dose
Route
Ophthalmic
Frequency
q12h
🐈

Cat

Use 0
Dose
Route
Ophthalmic
Frequency
q12h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature, protect from light

Safety

Monitoring parameters

IOPHeart rate (systemic beta-blockade)Respiratory effort (asthmatic patients — AVOID)Schirmer tear test
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Timoptic
Merck
Betimol

FAQs

Frequently asked questions

What is Timolol Ophthalmic?
Timolol Ophthalmic is a ophthalmic non-selective beta-blocker used in pets. Non-selective beta-1/beta-2 adrenergic antagonist that reduces aqueous humor production by the ciliary body (beta-2 receptor blockade decreases cAMP-mediated aqueous secretion). Lowers IOP ~20–25% without affecting pupil size or accommodation.
What is Timolol Ophthalmic used for in pets?
Timolol Ophthalmic is used in veterinary medicine for: Used for chronic glaucoma — often combined with dorzolamide (Cosopt = dorzolamid; Use 0.
What is the Timolol Ophthalmic dose for dogs?
For dogs, Timolol Ophthalmic is typically dosed as follows — Used for chronic glaucoma — often combined with dorzolamide (Cosopt = dorzolamid: undefined undefined Ophthalmic q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Timolol Ophthalmic dose for cats?
For cats, Timolol Ophthalmic is typically dosed as follows — Use 0: undefined undefined Ophthalmic q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Timolol Ophthalmic need a prescription?
Yes. Timolol Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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