Synergistic combination: sulfadimethoxine inhibits DHPS and ormetoprim inhibits DHFR (same sequential folate blockade as TMP-sulfa). Long half-life allows once-daily dosing. FDA-approved for dogs.
At a glance
Class
Potentiated Sulfonamide Antibiotic
Storage
Store at room temperature below 30°C
Dosing
FDA-approved for canine skin infections and UTIs
Frequency
q24h (after loading)
Sulfadimethoxine alone (Albon) is used in cats for coccidiosis at different dose
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Schirmer tear testCBCUrinalysis (hydration)Hepatic enzymesThyroid function (chronic)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Sulfadimethoxine/Ormetoprim?
Sulfadimethoxine/Ormetoprim is a potentiated sulfonamide antibiotic used in pets. Synergistic combination: sulfadimethoxine inhibits DHPS and ormetoprim inhibits DHFR (same sequential folate blockade as TMP-sulfa). Long half-life allows once-daily dosing. FDA-approved for dogs.
›What is Sulfadimethoxine/Ormetoprim used for in pets?
Sulfadimethoxine/Ormetoprim is used in veterinary medicine for: FDA-approved for canine skin infections and UTIs; Sulfadimethoxine alone (Albon) is used in cats for coccidiosis at different dose.
›What is the Sulfadimethoxine/Ormetoprim dose for dogs?
For dogs, Sulfadimethoxine/Ormetoprim is typically dosed as follows — FDA-approved for canine skin infections and UTIs: 55 mg/kg PO q24h (after loading). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Sulfadimethoxine/Ormetoprim dose for cats?
For cats, Sulfadimethoxine/Ormetoprim is typically dosed as follows — Sulfadimethoxine alone (Albon) is used in cats for coccidiosis at different dose: undefined undefined N/A N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Sulfadimethoxine/Ormetoprim need a prescription?
Yes. Sulfadimethoxine/Ormetoprim is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database