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Sodium Chloride Ophthalmic (Hypertonic 5%)

Ophthalmic Hyperosmotic Agent
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
2

Mechanism of action

5% hypertonic sodium chloride creates an osmotic gradient that draws fluid from the edematous corneal stroma into the tear film, reducing corneal edema and improving clarity. Used for corneal endothelial dysfunction.

At a glance

Class
Ophthalmic Hyperosmotic Agent
Schedule
OTC
Storage
Store at room temperature

Dosing

🐕

Dog

Used for corneal edema (endothelial dystrophy, post-cataract surgery corneal ede
Dose
Route
Ophthalmic
Frequency
q4–8h
🐈

Cat

Used for corneal endothelial disease and post-surgical edema
Dose
Route
Ophthalmic
Frequency
q4–8h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature

Safety

Monitoring parameters

Corneal clarity improvementCorneal pachymetry (thickness) if availablePatient comfort
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Muro 128
Bausch+Lomb

FAQs

Frequently asked questions

What is Sodium Chloride Ophthalmic (Hypertonic 5%)?
Sodium Chloride Ophthalmic (Hypertonic 5%) is a ophthalmic hyperosmotic agent used in pets. 5% hypertonic sodium chloride creates an osmotic gradient that draws fluid from the edematous corneal stroma into the tear film, reducing corneal edema and improving clarity. Used for corneal endothelial dysfunction.
What is Sodium Chloride Ophthalmic (Hypertonic 5%) used for in pets?
Sodium Chloride Ophthalmic (Hypertonic 5%) is used in veterinary medicine for: Used for corneal edema (endothelial dystrophy, post-cataract surgery corneal ede; Used for corneal endothelial disease and post-surgical edema.
What is the Sodium Chloride Ophthalmic (Hypertonic 5%) dose for dogs?
For dogs, Sodium Chloride Ophthalmic (Hypertonic 5%) is typically dosed as follows — Used for corneal edema (endothelial dystrophy, post-cataract surgery corneal ede: undefined undefined Ophthalmic q4–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Sodium Chloride Ophthalmic (Hypertonic 5%) dose for cats?
For cats, Sodium Chloride Ophthalmic (Hypertonic 5%) is typically dosed as follows — Used for corneal endothelial disease and post-surgical edema: undefined undefined Ophthalmic q4–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Sodium Chloride Ophthalmic (Hypertonic 5%) need a prescription?
Sodium Chloride Ophthalmic (Hypertonic 5%) is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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