5% hypertonic sodium chloride creates an osmotic gradient that draws fluid from the edematous corneal stroma into the tear film, reducing corneal edema and improving clarity. Used for corneal endothelial dysfunction.
At a glance
Class
Ophthalmic Hyperosmotic Agent
Storage
Store at room temperature
Dosing
Used for corneal edema (endothelial dystrophy, post-cataract surgery corneal ede
Used for corneal endothelial disease and post-surgical edema
Safety
Corneal clarity improvementCorneal pachymetry (thickness) if availablePatient comfort
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Sodium Chloride Ophthalmic (Hypertonic 5%)?
Sodium Chloride Ophthalmic (Hypertonic 5%) is a ophthalmic hyperosmotic agent used in pets. 5% hypertonic sodium chloride creates an osmotic gradient that draws fluid from the edematous corneal stroma into the tear film, reducing corneal edema and improving clarity. Used for corneal endothelial dysfunction.
›What is Sodium Chloride Ophthalmic (Hypertonic 5%) used for in pets?
Sodium Chloride Ophthalmic (Hypertonic 5%) is used in veterinary medicine for: Used for corneal edema (endothelial dystrophy, post-cataract surgery corneal ede; Used for corneal endothelial disease and post-surgical edema.
›What is the Sodium Chloride Ophthalmic (Hypertonic 5%) dose for dogs?
For dogs, Sodium Chloride Ophthalmic (Hypertonic 5%) is typically dosed as follows — Used for corneal edema (endothelial dystrophy, post-cataract surgery corneal ede: undefined undefined Ophthalmic q4–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Sodium Chloride Ophthalmic (Hypertonic 5%) dose for cats?
For cats, Sodium Chloride Ophthalmic (Hypertonic 5%) is typically dosed as follows — Used for corneal endothelial disease and post-surgical edema: undefined undefined Ophthalmic q4–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Sodium Chloride Ophthalmic (Hypertonic 5%) need a prescription?
Sodium Chloride Ophthalmic (Hypertonic 5%) is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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