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Secnidazole

Prescription
Nitroimidazole Antiprotozoal
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

5-nitroimidazole derivative that is reduced intracellularly by microbial ferredoxin-linked enzymes, generating toxic radical species that damage microbial DNA. Longer half-life than metronidazole allowing single-dose therapy.

At a glance

Class
Nitroimidazole Antiprotozoal
Schedule
Prescription
Storage
Store at room temperature below 30°C

Dosing

🐕

Dog

Longer half-life than metronidazole; used for giardiasis and trichomoniasis
Dose
25 mg/kg
Route
PO
Frequency
Once or q24h x 3 days
🐈

Cat

Limited veterinary data
Dose
25 mg/kg
Route
PO
Frequency
Once
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature below 30°C

Safety

Monitoring parameters

Neurological signs with prolonged useLiver enzymes
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Solosec
Secnil

FAQs

Frequently asked questions

What is Secnidazole?
Secnidazole is a nitroimidazole antiprotozoal used in pets. 5-nitroimidazole derivative that is reduced intracellularly by microbial ferredoxin-linked enzymes, generating toxic radical species that damage microbial DNA. Longer half-life than metronidazole allowing single-dose therapy.
What is Secnidazole used for in pets?
Secnidazole is used in veterinary medicine for: Longer half-life than metronidazole; used for giardiasis and trichomoniasis; Limited veterinary data.
What is the Secnidazole dose for dogs?
For dogs, Secnidazole is typically dosed as follows — Longer half-life than metronidazole; used for giardiasis and trichomoniasis: 25 mg/kg PO Once or q24h x 3 days. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Secnidazole dose for cats?
For cats, Secnidazole is typically dosed as follows — Limited veterinary data: 25 mg/kg PO Once. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Secnidazole need a prescription?
Yes. Secnidazole is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Nitroimidazole Antiprotozoal).

Ronidazole
Rx
5-nitroimidazole that is reduced intracellularly by anaerobic organisms, generating cytotoxic radicals that damage DNA and protein synthesis. Specifically active against Tritrichomonas foetus — the only effective treatment for this organism in cats.
dogcat
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