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Ropivacaine

Prescription
Long-Acting Amide Local Anesthetic
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

S-enantiomer of bupivacaine with similar duration (4–8h) but significantly less cardiac toxicity. Blocks voltage-gated sodium channels. Greater sensory-motor differentiation — preferentially blocks sensory over motor fibers at lower concentrations.

At a glance

Class
Long-Acting Amide Local Anesthetic
Schedule
Prescription
Storage
Store at room temperature below 25°C, protect from light

Dosing

🐕

Dog

Safer alternative to bupivacaine for regional anesthesia — less cardiotoxic
Dose
1–1.5 mg/kg
Route
Local infiltration, Epidural, Nerve block
Frequency
Single administration; duration 4–8h
🐈

Cat

Safer than bupivacaine in cats
Dose
Route
Local infiltration, Nerve block
Frequency
Single administration
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature below 25°C, protect from light

Safety

Monitoring parameters

Total dose calculationSigns of systemic toxicityMotor function (expected block with higher concentrations)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Naropin

FAQs

Frequently asked questions

What is Ropivacaine?
Ropivacaine is a long-acting amide local anesthetic used in pets. S-enantiomer of bupivacaine with similar duration (4–8h) but significantly less cardiac toxicity. Blocks voltage-gated sodium channels. Greater sensory-motor differentiation — preferentially blocks sensory over motor fibers at lower concentrations.
What is Ropivacaine used for in pets?
Ropivacaine is used in veterinary medicine for: Safer alternative to bupivacaine for regional anesthesia — less cardiotoxic; Safer than bupivacaine in cats.
What is the Ropivacaine dose for dogs?
For dogs, Ropivacaine is typically dosed as follows — Safer alternative to bupivacaine for regional anesthesia — less cardiotoxic: 1–1.5 mg/kg Local infiltration/Epidural/Nerve block Single administration; duration 4–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Ropivacaine dose for cats?
For cats, Ropivacaine is typically dosed as follows — Safer than bupivacaine in cats: undefined undefined Local infiltration/Nerve block Single administration. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Ropivacaine need a prescription?
Yes. Ropivacaine is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Long-Acting Amide Local Anesthetic).

Bupivacaine
Rx
Blocks voltage-gated sodium channels in nerve fibers, preventing initiation and propagation of nerve impulses; longer duration of action than lidocaine due to higher protein binding and lipophilicity
dogcat
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