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Ropinirole

Prescription
Dopamine D2/D3 Receptor Agonist / Emetic
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Selective dopamine D2/D3 receptor agonist that activates the chemoreceptor trigger zone (CTZ) and vomiting center when applied to the conjunctival mucosa, inducing emesis within minutes. First FDA-approved ophthalmic emetic for dogs.

At a glance

Class
Dopamine D2/D3 Receptor Agonist / Emetic
Schedule
Prescription
Storage
Refrigerate 2–8°C; single-use — discard after use

Dosing

🐕

Dog

FDA-approved ocular emetic for dogs
Dose
Route
PO
Frequency
Once; repeat once if needed
🐈

Cat

Not approved or studied in cats
Dose
Route
N, A
Frequency
N/A
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Refrigerate 2–8°C; single-use — discard after use

Safety

Monitoring parameters

Emesis within 20 minVolume and content of emesisEye irritation (rinse post-vomiting)Vitals for 30 min
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

US/EU

Clevor
Elanco

FAQs

Frequently asked questions

What is Ropinirole?
Ropinirole is a dopamine d2/d3 receptor agonist / emetic used in pets. Selective dopamine D2/D3 receptor agonist that activates the chemoreceptor trigger zone (CTZ) and vomiting center when applied to the conjunctival mucosa, inducing emesis within minutes. First FDA-approved ophthalmic emetic for dogs.
What is Ropinirole used for in pets?
Ropinirole is used in veterinary medicine for: FDA-approved ocular emetic for dogs; Not approved or studied in cats.
What is the Ropinirole dose for dogs?
For dogs, Ropinirole is typically dosed as follows — FDA-approved ocular emetic for dogs: undefined undefined PO Once; repeat once if needed. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Ropinirole dose for cats?
For cats, Ropinirole is typically dosed as follows — Not approved or studied in cats: undefined undefined N/A N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Ropinirole need a prescription?
Yes. Ropinirole is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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