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Robenacoxib

PrescriptionCDSCO approved
COX-2 selective NSAID (coxib)
Last reviewed 19 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Interactions
1 documented
Formulations
5

Mechanism of action

Highly selective COX-2 inhibitor at inflamed tissue, sparing COX-1 mediated protective prostaglandins in the GI tract and kidneys; rapid onset of action

At a glance

Class
COX-2 selective NSAID (coxib)
Schedule
Prescription
Storage
Store below 25°C
CDSCO (India)
Vet-approved — 2012-01

Dosing

🐕

Dog

Pain and inflammation (surgical, osteoarthritis)
Dose
1–2 mg/kg
Route
PO, SC
Frequency
SID
Max dose
40 mg
Duration: SC: up to 3 days perioperative; PO: long-term for OA
🐈

Cat

Perioperative pain / Acute musculoskeletal pain
Dose
1–2 mg/kg
Route
PO, SC
Frequency
SID
Max dose
6 mg
Duration: SC: single dose; PO: up to 6 days (labeled); longer off-label with monitoring
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Tablet — 4

Strength
6mg
Strength
10mg
Strength
20mg
Strength
40mg
💉

Injection — 1

Strength
20mg/mL

Storage

Store below 25°C

Safety

Absolute contraindications — do not use

  • GI ulceration or bleeding
  • Severe renal or hepatic impairment
  • Concurrent corticosteroids or other NSAIDs
    PrednisoloneMeloxicamCarprofen

Use with caution

  • Dehydration or hypovolemia
    Correct fluid status first

Adverse effects

Common
Vomiting
Diarrhoea
Soft stools
Serious
GI ulceration
Renal injury
Hepatotoxicity

Monitoring parameters

Renal values (BUN, creatinine)Hepatic enzymesGI signsHydration status
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

Contraindicated — 1

Meloxicam
contraindicated
Two NSAIDs: additive prostaglandin inhibition causing GI hemorrhage and renal failure.
Management: Never combine. Allow 3-5 day washout when switching NSAIDs.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Brands

International

Onsior
Elanco

FAQs

Frequently asked questions

What is Robenacoxib?
Robenacoxib is a cox-2 selective nsaid (coxib) used in pets. Highly selective COX-2 inhibitor at inflamed tissue, sparing COX-1 mediated protective prostaglandins in the GI tract and kidneys; rapid onset of action
What is Robenacoxib used for in pets?
Robenacoxib is used in veterinary medicine for: Pain and inflammation (surgical, osteoarthritis); Perioperative pain / Acute musculoskeletal pain.
What is the Robenacoxib dose for dogs?
For dogs, Robenacoxib is typically dosed as follows — Pain and inflammation (surgical, osteoarthritis): 1–2 mg/kg PO/SC SID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Robenacoxib dose for cats?
For cats, Robenacoxib is typically dosed as follows — Perioperative pain / Acute musculoskeletal pain: 1–2 mg/kg PO/SC SID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What are the side effects of Robenacoxib?
Common: Vomiting, Diarrhoea, Soft stools. Serious (call your vet immediately): GI ulceration, Renal injury, Hepatotoxicity.
Does Robenacoxib need a prescription?
Yes. Robenacoxib is a prescription medication and should only be administered under veterinary supervision.
When should Robenacoxib not be used?
Do not use Robenacoxib if: GI ulceration or bleeding; Severe renal or hepatic impairment; Concurrent corticosteroids or other NSAIDs.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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