Direct, selective, reversible inhibitor of Factor Xa (both free and clot-bound), blocking the conversion of prothrombin to thrombin. Oral with predictable pharmacokinetics — no monitoring required in humans. Fixed dosing.
At a glance
Class
Direct Oral Anticoagulant (Factor Xa Inhibitor)
Storage
Store at room temperature below 30°C
Dosing
Emerging veterinary use for thromboembolic disease (IMHA, PLE, cardiac disease)
Investigational for feline ATE prevention
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Anti-Xa activity (calibrated for rivaroxaban — if available)Clinical bleeding signsRenal functionHepatic function
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Rivaroxaban?
Rivaroxaban is a direct oral anticoagulant (factor xa inhibitor) used in pets. Direct, selective, reversible inhibitor of Factor Xa (both free and clot-bound), blocking the conversion of prothrombin to thrombin. Oral with predictable pharmacokinetics — no monitoring required in humans. Fixed dosing.
›What is Rivaroxaban used for in pets?
Rivaroxaban is used in veterinary medicine for: Emerging veterinary use for thromboembolic disease (IMHA, PLE, cardiac disease); Investigational for feline ATE prevention.
›What is the Rivaroxaban dose for dogs?
For dogs, Rivaroxaban is typically dosed as follows — Emerging veterinary use for thromboembolic disease (IMHA, PLE, cardiac disease): 1–2 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Rivaroxaban dose for cats?
For cats, Rivaroxaban is typically dosed as follows — Investigational for feline ATE prevention: 1–2 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Rivaroxaban need a prescription?
Yes. Rivaroxaban is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database