Double prodrug that releases the active nucleotide analog PMEG intracellularly. PMEG is incorporated into DNA by DNA polymerases, causing chain termination and apoptosis. Designed specifically for canine lymphoma.
At a glance
Class
Nucleotide Analog (Chemotherapy)
Schedule
Prescription (Chemotherapy)
Storage
Refrigerate 2–8°C; diluted solution use within 4h; chemotherapy precautions
Dosing
FDA-conditionally approved for canine lymphoma (T-cell and B-cell)
Frequency
q3 weeks x 5 doses
Not approved or studied in cats
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Thoracic radiographs before each dose (pulmonary fibrosis screening)CBC at nadir and before each doseHepatic enzymesSkin assessmentRespiratory rate and effort
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Rabacfosadine?
Rabacfosadine is a nucleotide analog (chemotherapy) used in pets. Double prodrug that releases the active nucleotide analog PMEG intracellularly. PMEG is incorporated into DNA by DNA polymerases, causing chain termination and apoptosis. Designed specifically for canine lymphoma.
›What is Rabacfosadine used for in pets?
Rabacfosadine is used in veterinary medicine for: FDA-conditionally approved for canine lymphoma (T-cell and B-cell); Not approved or studied in cats.
›What is the Rabacfosadine dose for dogs?
For dogs, Rabacfosadine is typically dosed as follows — FDA-conditionally approved for canine lymphoma (T-cell and B-cell): 1 mg/kg PO q3 weeks x 5 doses. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Rabacfosadine dose for cats?
For cats, Rabacfosadine is typically dosed as follows — Not approved or studied in cats: undefined undefined N/A N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Rabacfosadine need a prescription?
Yes. Rabacfosadine is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database