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Pyrantel Pamoate

PrescriptionCDSCO approved
Tetrahydropyrimidine anthelmintic
Last reviewed 18 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
3 available
Formulations
3

Mechanism of action

Depolarising neuromuscular blocking agent — causes spastic paralysis of nematodes by acting as a cholinergic agonist at nicotinic receptors

At a glance

Class
Tetrahydropyrimidine anthelmintic
Schedule
Prescription
Storage
Store below 25°C
CDSCO (India)
Vet-approved — 1969-04

Dosing

🐕

Dog

Roundworms (Toxocara, Toxascaris)
Dose
5–10 mg/kg
Route
PO
Frequency
Single dose
Max dose
500 mg
Duration: Repeat in 2-3 weeks; puppies: every 2 weeks from 2 weeks age until 12 weeks
Hookworms (Ancylostoma)
Dose
5–10 mg/kg
Route
PO
Frequency
Single dose, repeat in 2-3 weeks
Max dose
500 mg
Duration: Repeat dosing to clear larvae
🐈

Cat

Roundworms and hookworms
Dose
5–10 mg/kg
Route
PO
Frequency
Single dose, repeat in 2-3 weeks
Max dose
100 mg
Duration: Kittens: every 2 weeks from 3 weeks age until 12 weeks
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

🧴

Suspension — 1

Strength
50mg/mL
Available in India
💊

Tablet — 2

Strength
125mg
Available in India
Strength
250mg
Available in India

Storage

Store below 25°C

Safety

Absolute contraindications — do not use

  • Concurrent organophosphate/levamisole use
    Synergistic cholinergic toxicity — cholinergic crisis risk
    LevamisoleOrganophosphates

Use with caution

  • Severe debilitation
    Severely debilitated animals — stabilise before deworming
  • Hepatic impairment
    Minimal systemic absorption but caution advised

Adverse effects

Common
Vomiting
Mild diarrhoea
Serious
Cholinergic signs if overdosed (salivation, muscle tremors)

Monitoring parameters

Faecal examination 2-3 weeks post-treatment
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

International

Strongid
Zoetis

India

Nemocid
Pfizer/GSK
Pyranvet
Intas

FAQs

Frequently asked questions

What is Pyrantel Pamoate?
Pyrantel Pamoate is a tetrahydropyrimidine anthelmintic used in pets. Depolarising neuromuscular blocking agent — causes spastic paralysis of nematodes by acting as a cholinergic agonist at nicotinic receptors
What is Pyrantel Pamoate used for in pets?
Pyrantel Pamoate is used in veterinary medicine for: Roundworms (Toxocara, Toxascaris); Hookworms (Ancylostoma); Roundworms and hookworms.
What is the Pyrantel Pamoate dose for dogs?
For dogs, Pyrantel Pamoate is typically dosed as follows — Roundworms (Toxocara, Toxascaris): 5–10 mg/kg PO Single dose; Hookworms (Ancylostoma): 5–10 mg/kg PO Single dose, repeat in 2-3 weeks. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Pyrantel Pamoate dose for cats?
For cats, Pyrantel Pamoate is typically dosed as follows — Roundworms and hookworms: 5–10 mg/kg PO Single dose, repeat in 2-3 weeks. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What are the side effects of Pyrantel Pamoate?
Common: Vomiting, Mild diarrhoea. Serious (call your vet immediately): Cholinergic signs if overdosed (salivation, muscle tremors).
Does Pyrantel Pamoate need a prescription?
Yes. Pyrantel Pamoate is a prescription medication and should only be administered under veterinary supervision.
When should Pyrantel Pamoate not be used?
Do not use Pyrantel Pamoate if: Concurrent organophosphate/levamisole use.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

CDSCO approvals (India) — 6

Pyrantel Tartrate
M/s Pfizer Private Limited · Approved 1969 April
In the treatment if infestation with G.I round Worm in Sheep, Cattle & swine (Broad Spectrum Anthelmintic)
3-Methyl Pyrantel Tartrate
M/s Pfizer Private Limited Bombay · Approved 1970. May
Pyrantel embonate with fabental suspension
M/s Bayer India Limited · Approved 23.04.2001
for treatment of infestation caused by round worms, ascarids hook worms whip worm in puppies and young dogs.
Praziquntel 175mg + Pyrantel 504mg + Febental 525mg Tablets
Mm/s Bayer Healthcare · Approved 30.03.2010
For the Treatment of mixed infections with roundworms and tapeworms in dogs
Praziquantal 20mg +Pyrantel embonate 230 mg
M/s Bayer Pharmaceuticals Pvt Ltd · Approved 25.11.2013
for the treatment mixed infestations with roundworms and tapeworms in dogs
Praziquantal 20mg+Pyrantel embonate 230mg Tablet ( Veterinary product)
M/s. Bayer Healthcare · Approved 25.11.2013
For the treatment mixed infestations with roundworms and tapeworms in Dogs
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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