›What is Protamine Sulfate?
Protamine Sulfate is a heparin antagonist used in pets. Positively charged protein derived from salmon sperm that binds ionically to negatively charged heparin molecules, forming a stable heparin-protamine complex that is pharmacologically inactive, reversing heparin anticoagulation within minutes.
›What is Protamine Sulfate used for in pets?
Protamine Sulfate is used in veterinary medicine for: Only for reversing unfractionated heparin overdose or post-procedural hepariniza; Rarely needed in clinical feline practice.
›What is the Protamine Sulfate dose for dogs?
For dogs, Protamine Sulfate is typically dosed as follows — Only for reversing unfractionated heparin overdose or post-procedural hepariniza: undefined undefined PO Single dose; may repeat 50% dose if aPTT still prolonged after 30 min. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Protamine Sulfate dose for cats?
For cats, Protamine Sulfate is typically dosed as follows — Rarely needed in clinical feline practice: undefined undefined IV Single dose. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Protamine Sulfate need a prescription?
Yes. Protamine Sulfate is a prescription medication and should only be administered under veterinary supervision.