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Probiotics (Enterococcus faecium SF68)

Probiotic supplement (live microorganism)
Last reviewed 19 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
5 available
Formulations
4

Mechanism of action

Provides beneficial live microorganisms (Enterococcus faecium SF68) that colonise the GI tract, competing with pathogens, modulating immune function, and restoring normal gut microbiome balance

At a glance

Class
Probiotic supplement (live microorganism)
Schedule
OTC
Storage
Store below 25°C in a cool, dry place. Some formulations require refrigeration — check label. Do not expose to heat or moisture.

Dosing

🐕

Dog

Diarrhoea (acute, antibiotic-associated, dietary)
Dose
1 sachet per day
Route
PO (sprinkled on food)
Frequency
SID
Max dose
1 sachet
Duration: 5-7 days (acute) or ongoing as maintenance
GI microbiome support during antibiotics
Dose
1 sachet per day
Route
PO (sprinkled on food)
Frequency
SID
Max dose
1 sachet
Duration: Duration of antibiotic course + 5-7 days after
🐈

Cat

Diarrhoea (acute, antibiotic-associated)
Dose
1 sachet per day
Route
PO (sprinkled on food)
Frequency
SID
Max dose
1 sachet
Duration: 5-7 days or ongoing
Chronic inflammatory bowel disease (adjunct)
Dose
1 sachet per day
Route
PO (sprinkled on food)
Frequency
SID
Max dose
1 sachet
Duration: Long-term

Formulations

💊

Powder sachet (canine) — 1

Strength
1g sachet (>1×10^8 CFU/g)
Available in India
💊

Powder sachet (feline) — 1

Strength
1g sachet (>5×10^8 CFU/g)
Available in India
💊

Chewable tablet — 1

Strength
1 tablet (>1×10^8 CFU)
Available in India
💊

Paste (pro-kolin) — 1

Strength
15mL/30mL syringe
Available in India

Storage

Store below 25°C in a cool, dry place. Some formulations require refrigeration — check label. Do not expose to heat or moisture.

Safety

Use with caution

  • Severely immunocompromised patients
    Theoretical risk of bacteraemia from live organisms in severely immunocompromised patients — rare but documented in humans
  • Central venous catheter in place
    Theoretical translocation risk — minimal in practice

Adverse effects

Common
Generally very well tolerated
Mild gas/flatulence (initial)
Serious
Bacteraemia (extremely rare — severely immunocompromised only)

Monitoring parameters

Stool consistencyAppetiteBody weightClinical response

Interactions

No documented interactions.

Brands

International

FortiFlora
Purina Pro Plan
Pro-Kolin
Protexin

India

FortiFlora
Purina Pro Plan
Gutwell
Intas
Vibact
USV

FAQs

Frequently asked questions

What is Probiotics (Enterococcus faecium SF68)?
Probiotics (Enterococcus faecium SF68) is a probiotic supplement (live microorganism) used in pets. Provides beneficial live microorganisms (Enterococcus faecium SF68) that colonise the GI tract, competing with pathogens, modulating immune function, and restoring normal gut microbiome balance
What is Probiotics (Enterococcus faecium SF68) used for in pets?
Probiotics (Enterococcus faecium SF68) is used in veterinary medicine for: Diarrhoea (acute, antibiotic-associated, dietary); GI microbiome support during antibiotics; Diarrhoea (acute, antibiotic-associated); Chronic inflammatory bowel disease (adjunct).
What is the Probiotics (Enterococcus faecium SF68) dose for dogs?
For dogs, Probiotics (Enterococcus faecium SF68) is typically dosed as follows — Diarrhoea (acute, antibiotic-associated, dietary): 1 sachet per day PO (sprinkled on food) SID; GI microbiome support during antibiotics: 1 sachet per day PO (sprinkled on food) SID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Probiotics (Enterococcus faecium SF68) dose for cats?
For cats, Probiotics (Enterococcus faecium SF68) is typically dosed as follows — Diarrhoea (acute, antibiotic-associated): 1 sachet per day PO (sprinkled on food) SID; Chronic inflammatory bowel disease (adjunct): 1 sachet per day PO (sprinkled on food) SID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What are the side effects of Probiotics (Enterococcus faecium SF68)?
Common: Generally very well tolerated, Mild gas/flatulence (initial). Serious (call your vet immediately): Bacteraemia (extremely rare — severely immunocompromised only).
Does Probiotics (Enterococcus faecium SF68) need a prescription?
Probiotics (Enterococcus faecium SF68) is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.

References

References

Textbooks & handbooks

  • Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
  • Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
  • Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
  • National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
  • The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/

Clinical guidelines & consensus

  • Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
  • American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.

Journals & peer-reviewed studies

  • Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
  • Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
  • ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control

Regulatory & approvals

  • Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/

Databases

  • Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →