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Prednisolone Ophthalmic

Prescription
Ophthalmic Corticosteroid
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

Potent glucocorticoid acetate suspension that suppresses inflammatory and immune responses in ocular tissues. Reduces vascular permeability, fibrin deposition, cellular infiltration, and neovascularization. Acetate form penetrates intact corneal epithelium well.

At a glance

Class
Ophthalmic Corticosteroid
Schedule
Prescription
Storage
Store at room temperature; shake well before use

Dosing

🐕

Dog

Workhorse ophthalmic steroid for anterior uveitis, immune-mediated keratitis, an
Dose
Route
Ophthalmic
Frequency
q4–12h (taper)
🐈

Cat

Same indications
Dose
Route
Ophthalmic
Frequency
q6–12h

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature; shake well before use

Safety

Monitoring parameters

IOP at 2 weeks (steroid-induced glaucoma)Fluorescein stain before each refillTaper — never stop abruptly (rebound inflammation)

Interactions

No documented interactions.

Brands

Other markets

Pred Forte
Allergan
Pred Mild

FAQs

Frequently asked questions

What is Prednisolone Ophthalmic?
Prednisolone Ophthalmic is a ophthalmic corticosteroid used in pets. Potent glucocorticoid acetate suspension that suppresses inflammatory and immune responses in ocular tissues. Reduces vascular permeability, fibrin deposition, cellular infiltration, and neovascularization. Acetate form penetrates intact corneal epithelium well.
What is Prednisolone Ophthalmic used for in pets?
Prednisolone Ophthalmic is used in veterinary medicine for: Workhorse ophthalmic steroid for anterior uveitis, immune-mediated keratitis, an; Same indications.
What is the Prednisolone Ophthalmic dose for dogs?
For dogs, Prednisolone Ophthalmic is typically dosed as follows — Workhorse ophthalmic steroid for anterior uveitis, immune-mediated keratitis, an: undefined undefined Ophthalmic q4–12h (taper). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Prednisolone Ophthalmic dose for cats?
For cats, Prednisolone Ophthalmic is typically dosed as follows — Same indications: undefined undefined Ophthalmic q6–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Prednisolone Ophthalmic need a prescription?
Yes. Prednisolone Ophthalmic is a prescription medication and should only be administered under veterinary supervision.

References

References

Textbooks & handbooks

  • Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
  • Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
  • Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
  • National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
  • The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/

Clinical guidelines & consensus

  • Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
  • American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.

Journals & peer-reviewed studies

  • Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
  • Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
  • ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control

Regulatory & approvals

  • Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/

Databases

  • Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

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