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Prednisolone Ophthalmic

Prescription
Ophthalmic Corticosteroid
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

Potent glucocorticoid acetate suspension that suppresses inflammatory and immune responses in ocular tissues. Reduces vascular permeability, fibrin deposition, cellular infiltration, and neovascularization. Acetate form penetrates intact corneal epithelium well.

At a glance

Class
Ophthalmic Corticosteroid
Schedule
Prescription
Storage
Store at room temperature; shake well before use

Dosing

🐕

Dog

Workhorse ophthalmic steroid for anterior uveitis, immune-mediated keratitis, an
Dose
Route
Ophthalmic
Frequency
q4–12h (taper)
🐈

Cat

Same indications
Dose
Route
Ophthalmic
Frequency
q6–12h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature; shake well before use

Safety

Monitoring parameters

IOP at 2 weeks (steroid-induced glaucoma)Fluorescein stain before each refillTaper — never stop abruptly (rebound inflammation)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Pred Forte
Allergan
Pred Mild

FAQs

Frequently asked questions

What is Prednisolone Ophthalmic?
Prednisolone Ophthalmic is a ophthalmic corticosteroid used in pets. Potent glucocorticoid acetate suspension that suppresses inflammatory and immune responses in ocular tissues. Reduces vascular permeability, fibrin deposition, cellular infiltration, and neovascularization. Acetate form penetrates intact corneal epithelium well.
What is Prednisolone Ophthalmic used for in pets?
Prednisolone Ophthalmic is used in veterinary medicine for: Workhorse ophthalmic steroid for anterior uveitis, immune-mediated keratitis, an; Same indications.
What is the Prednisolone Ophthalmic dose for dogs?
For dogs, Prednisolone Ophthalmic is typically dosed as follows — Workhorse ophthalmic steroid for anterior uveitis, immune-mediated keratitis, an: undefined undefined Ophthalmic q4–12h (taper). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Prednisolone Ophthalmic dose for cats?
For cats, Prednisolone Ophthalmic is typically dosed as follows — Same indications: undefined undefined Ophthalmic q6–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Prednisolone Ophthalmic need a prescription?
Yes. Prednisolone Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Ophthalmic Corticosteroid).

Dexamethasone (Ophthalmic)
Rx
Potent glucocorticoid that suppresses inflammatory cytokines, prostaglandins, and cellular immune responses in ocular tissues. Reduces protein exudation, vascular permeability, and fibrin deposition.
dogcat
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