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Pradofloxacin

Prescription
Third-Generation Veterinary Fluoroquinolone
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
2

Mechanism of action

Dual-targeting fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV with equal potency (dual-target inhibition), reducing resistance development. Broader spectrum than enrofloxacin/marbofloxacin including enhanced anaerobic coverage.

At a glance

Class
Third-Generation Veterinary Fluoroquinolone
Schedule
Prescription
Storage
Oral suspension at room temperature; use within 3 months of opening

Dosing

🐕

Dog

EU-approved for dogs
Dose
3–4.5 mg/kg
Route
PO
Frequency
q24h
🐈

Cat

FDA-approved (US) for feline skin infections and wounds
Dose
5 mg/kg
Route
PO
Frequency
q24h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Oral suspension at room temperature; use within 3 months of opening

Safety

Monitoring parameters

Clinical responseRetinal exam in cats with prolonged useCulture and sensitivity
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Veraflox

FAQs

Frequently asked questions

What is Pradofloxacin?
Pradofloxacin is a third-generation veterinary fluoroquinolone used in pets. Dual-targeting fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV with equal potency (dual-target inhibition), reducing resistance development. Broader spectrum than enrofloxacin/marbofloxacin including enhanced anaerobic coverage.
What is Pradofloxacin used for in pets?
Pradofloxacin is used in veterinary medicine for: EU-approved for dogs; FDA-approved (US) for feline skin infections and wounds.
What is the Pradofloxacin dose for dogs?
For dogs, Pradofloxacin is typically dosed as follows — EU-approved for dogs: 3–4.5 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Pradofloxacin dose for cats?
For cats, Pradofloxacin is typically dosed as follows — FDA-approved (US) for feline skin infections and wounds: 5 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Pradofloxacin need a prescription?
Yes. Pradofloxacin is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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