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Potassium Iodide

Prescription
Iodine Supplement / Antithyroid Agent (Acute) / Antifungal
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
3

Mechanism of action

At high doses, iodide transiently inhibits thyroid hormone synthesis and release (Wolff-Chaikoff effect). Also has antifungal activity against Sporothrix schenckii by unknown mechanism. Used for thyroid storm and sporotrichosis.

At a glance

Class
Iodine Supplement / Antithyroid Agent (Acute) / Antifungal
Schedule
Prescription
Storage
Store at room temperature; SSKI protected from light (turns brown on exposure); stable for years

Dosing

🐕

Dog

Drug of choice for canine sporotrichosis (combined with itraconazole for resista
Dose
30–100 mg
Route
PO
Frequency
q8h
🐈

Cat

Cats are extremely sensitive to iodide toxicity (iodism)
Dose
Route
PO
Frequency
q12h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 3

Strength
Strength
Strength

Storage

Store at room temperature; SSKI protected from light (turns brown on exposure); stable for years

Safety

Monitoring parameters

Signs of iodism (salivation, vomiting, dandruff)Thyroid function (T4)Serum potassiumClinical fungal response at 4 weeks
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

SSKI
ThyroShield

FAQs

Frequently asked questions

What is Potassium Iodide?
Potassium Iodide is a iodine supplement / antithyroid agent (acute) / antifungal used in pets. At high doses, iodide transiently inhibits thyroid hormone synthesis and release (Wolff-Chaikoff effect). Also has antifungal activity against Sporothrix schenckii by unknown mechanism. Used for thyroid storm and sporotrichosis.
What is Potassium Iodide used for in pets?
Potassium Iodide is used in veterinary medicine for: Drug of choice for canine sporotrichosis (combined with itraconazole for resista; Cats are extremely sensitive to iodide toxicity (iodism).
What is the Potassium Iodide dose for dogs?
For dogs, Potassium Iodide is typically dosed as follows — Drug of choice for canine sporotrichosis (combined with itraconazole for resista: 30–100 mg PO q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Potassium Iodide dose for cats?
For cats, Potassium Iodide is typically dosed as follows — Cats are extremely sensitive to iodide toxicity (iodism): undefined undefined PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Potassium Iodide need a prescription?
Yes. Potassium Iodide is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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