Large polymer that is not absorbed or metabolized in the GI tract. Creates osmotic gradient retaining water in the colonic lumen, softening stool and increasing fecal volume, promoting defecation. Does not cause electrolyte disturbances at standard doses.
At a glance
Storage
Store at room temperature below 30°C
Dosing
Used for constipation and bowel prep
Route
PO (mixed in food, water)
Used for feline constipation and megacolon management
Safety
Stool frequency and consistencyHydration statusElectrolytes with prolonged high-dose use
Interactions
No documented interactions.
Brands
Other markets
GoLYTELY (with electrolytes)
FAQs
Frequently asked questions
›What is Polyethylene Glycol 3350 (PEG 3350)?
Polyethylene Glycol 3350 (PEG 3350) is a osmotic laxative used in pets. Large polymer that is not absorbed or metabolized in the GI tract. Creates osmotic gradient retaining water in the colonic lumen, softening stool and increasing fecal volume, promoting defecation. Does not cause electrolyte disturbances at standard doses.
›What is Polyethylene Glycol 3350 (PEG 3350) used for in pets?
Polyethylene Glycol 3350 (PEG 3350) is used in veterinary medicine for: Used for constipation and bowel prep; Used for feline constipation and megacolon management.
›What is the Polyethylene Glycol 3350 (PEG 3350) dose for dogs?
For dogs, Polyethylene Glycol 3350 (PEG 3350) is typically dosed as follows — Used for constipation and bowel prep: undefined undefined PO (mixed in food/water) q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Polyethylene Glycol 3350 (PEG 3350) dose for cats?
For cats, Polyethylene Glycol 3350 (PEG 3350) is typically dosed as follows — Used for feline constipation and megacolon management: undefined undefined PO q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Polyethylene Glycol 3350 (PEG 3350) need a prescription?
Polyethylene Glycol 3350 (PEG 3350) is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →