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Piroxicam

Prescription

Non-steroidal anti-inflammatory drug (NSAID) — Oxicam

Last reviewed 19 Apr 2026 · PetCare.AI Editorial Team

Species

Dog

Brands

3 available

Interactions

2 documented

Formulations

Mechanism of action

Non-selective COX inhibitor with anti-inflammatory, analgesic, and antipyretic properties; also used as anti-tumor agent due to anti-angiogenic effects in transitional cell carcinoma

At a glance

Class

Non-steroidal anti-inflammatory drug (NSAID) — Oxicam

Schedule

Prescription

Storage

Store below 25°C

Dosing

🐕

Dog

Transitional cell carcinoma (TCC) / Squamous cell carcinoma / Palliative anti-inflammatory

Dose

0.3 mg/kg

Route

Frequency

SID

Max dose

20 mg

Duration: Long-term for oncology; GI protectants recommended (misoprostol or PPI)

Educational reference only

This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Capsule — 2

Strength

10mg

Available in India

Strength

20mg

Available in India

Storage

Store below 25°C

Safety

Absolute contraindications — do not use

Cats (not recommended due to long half-life and toxicity)
Pre-existing GI ulceration or renal disease
Concurrent corticosteroids or other NSAIDs
GI hemorrhage risk
PrednisoloneDexamethasoneCarprofenMeloxicam

Adverse effects

Common

GI ulceration

Inappetence

Vomiting

Serious

GI perforation

Renal papillary necrosis

Hepatotoxicity

Monitoring parameters

BUN/CreatinineHepatic enzymesFecal occult bloodPCV

Educational reference only

Interactions

Contraindicated — 1

Meloxicam

contraindicated

Combined NSAID use dramatically increases GI ulceration, renal injury, and bleeding risk

Management: Never combine two NSAIDs. Allow 5-7 day washout when switching between NSAIDs.

Major — 1

Prednisolone

major

Combined NSAID + corticosteroid use greatly increases risk of GI ulceration and perforation

Management: Avoid concurrent use. If unavoidable, add GI protectant (omeprazole + sucralfate) and monitor for melena.

Educational reference only

Brands

International

Feldene

Pfizer

India

Pirox

Cipla

Dolonex

Pfizer India

FAQs

Frequently asked questions

›What is Piroxicam?

Piroxicam is a non-steroidal anti-inflammatory drug (nsaid) — oxicam used in pets. Non-selective COX inhibitor with anti-inflammatory, analgesic, and antipyretic properties; also used as anti-tumor agent due to anti-angiogenic effects in transitional cell carcinoma

›What is Piroxicam used for in pets?

Piroxicam is used in veterinary medicine for: Transitional cell carcinoma (TCC) / Squamous cell carcinoma / Palliative anti-inflammatory.

›What is the Piroxicam dose for dogs?

For dogs, Piroxicam is typically dosed as follows — Transitional cell carcinoma (TCC) / Squamous cell carcinoma / Palliative anti-inflammatory: 0.3 mg/kg PO SID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.

›What are the side effects of Piroxicam?

Common: GI ulceration, Inappetence, Vomiting. Serious (call your vet immediately): GI perforation, Renal papillary necrosis, Hepatotoxicity.

›Does Piroxicam need a prescription?

Yes. Piroxicam is a prescription medication and should only be administered under veterinary supervision.

›When should Piroxicam not be used?

Do not use Piroxicam if: Cats (not recommended due to long half-life and toxicity); Pre-existing GI ulceration or renal disease; Concurrent corticosteroids or other NSAIDs.

Educational reference only