Phenoxymethyl penicillin — acid-stable natural penicillin suitable for oral administration. Inhibits bacterial cell wall synthesis by binding PBPs. Narrow spectrum: streptococci, most anaerobes, and some gram-negatives. Susceptible to staphylococcal beta-lactamase.
At a glance
Class
Natural Penicillin (Oral)
Storage
Store at room temperature; oral solution refrigerated, use within 14 days
Dosing
Used for streptococcal infections, anaerobic infections, and prophylaxis
Used for streptococcal infections
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Clinical responseGI tolerance
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Penicillin V?
Penicillin V is a natural penicillin (oral) used in pets. Phenoxymethyl penicillin — acid-stable natural penicillin suitable for oral administration. Inhibits bacterial cell wall synthesis by binding PBPs. Narrow spectrum: streptococci, most anaerobes, and some gram-negatives. Susceptible to staphylococcal beta-lactamase.
›What is Penicillin V used for in pets?
Penicillin V is used in veterinary medicine for: Used for streptococcal infections, anaerobic infections, and prophylaxis; Used for streptococcal infections.
›What is the Penicillin V dose for dogs?
For dogs, Penicillin V is typically dosed as follows — Used for streptococcal infections, anaerobic infections, and prophylaxis: 10–30 mg/kg PO q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Penicillin V dose for cats?
For cats, Penicillin V is typically dosed as follows — Used for streptococcal infections: 10–15 mg/kg PO q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Penicillin V need a prescription?
Yes. Penicillin V is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database