Combination of porcine pancreatic lipase, protease (amylase, trypsin, chymotrypsin), and amylase that replaces or supplements deficient exocrine pancreatic secretions, enabling normal digestion of fats, proteins, and carbohydrates.
At a glance
Class
Pancreatic Enzyme Supplement
Storage
Store in a cool, dry place — moisture degrades enzymes; do not refrigerate unless specified
Dosing
Treatment for exocrine pancreatic insufficiency (EPI)
Route
PO (mixed with food)
Feline EPI less common than canine
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Body weightFecal consistency and fat content (fecal fat scoring)Cobalamin (B12) levels — often low in EPI
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Pancrelipase?
Pancrelipase is a pancreatic enzyme supplement used in pets. Combination of porcine pancreatic lipase, protease (amylase, trypsin, chymotrypsin), and amylase that replaces or supplements deficient exocrine pancreatic secretions, enabling normal digestion of fats, proteins, and carbohydrates.
›What is Pancrelipase used for in pets?
Pancrelipase is used in veterinary medicine for: Treatment for exocrine pancreatic insufficiency (EPI); Feline EPI less common than canine.
›What is the Pancrelipase dose for dogs?
For dogs, Pancrelipase is typically dosed as follows — Treatment for exocrine pancreatic insufficiency (EPI): undefined undefined PO (mixed with food) With each meal. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Pancrelipase dose for cats?
For cats, Pancrelipase is typically dosed as follows — Feline EPI less common than canine: undefined undefined PO With each meal. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Pancrelipase need a prescription?
Yes. Pancrelipase is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database