Combination of porcine pancreatic lipase, protease (amylase, trypsin, chymotrypsin), and amylase that replaces or supplements deficient exocrine pancreatic secretions, enabling normal digestion of fats, proteins, and carbohydrates.
At a glance
Class
Pancreatic Enzyme Supplement
Storage
Store in a cool, dry place — moisture degrades enzymes; do not refrigerate unless specified
Dosing
Treatment for exocrine pancreatic insufficiency (EPI)
Route
PO (mixed with food)
Feline EPI less common than canine
Safety
Body weightFecal consistency and fat content (fecal fat scoring)Cobalamin (B12) levels — often low in EPI
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Pancrelipase?
Pancrelipase is a pancreatic enzyme supplement used in pets. Combination of porcine pancreatic lipase, protease (amylase, trypsin, chymotrypsin), and amylase that replaces or supplements deficient exocrine pancreatic secretions, enabling normal digestion of fats, proteins, and carbohydrates.
›What is Pancrelipase used for in pets?
Pancrelipase is used in veterinary medicine for: Treatment for exocrine pancreatic insufficiency (EPI); Feline EPI less common than canine.
›What is the Pancrelipase dose for dogs?
For dogs, Pancrelipase is typically dosed as follows — Treatment for exocrine pancreatic insufficiency (EPI): undefined undefined PO (mixed with food) With each meal. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Pancrelipase dose for cats?
For cats, Pancrelipase is typically dosed as follows — Feline EPI less common than canine: undefined undefined PO With each meal. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Pancrelipase need a prescription?
Yes. Pancrelipase is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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