Oxytetracycline inhibits bacterial protein synthesis (30S ribosomal subunit) covering gram-positive, Chlamydophila, and Mycoplasma. Polymyxin B disrupts gram-negative cell membranes. Together provide broad-spectrum coverage for ocular infections.
At a glance
Class
Ophthalmic Combination Antibiotic
Storage
Store at room temperature below 25°C
Dosing
FDA-approved veterinary ophthalmic ointment
Effective for feline conjunctivitis
Safety
Clinical response at 5–7 daysCulture if no improvement
Interactions
No documented interactions.
Brands
United States
Terramycin Ophthalmic
Zoetis
FAQs
Frequently asked questions
›What is Oxytetracycline/Polymyxin B Ophthalmic?
Oxytetracycline/Polymyxin B Ophthalmic is a ophthalmic combination antibiotic used in pets. Oxytetracycline inhibits bacterial protein synthesis (30S ribosomal subunit) covering gram-positive, Chlamydophila, and Mycoplasma. Polymyxin B disrupts gram-negative cell membranes. Together provide broad-spectrum coverage for ocular infections.
›What is Oxytetracycline/Polymyxin B Ophthalmic used for in pets?
Oxytetracycline/Polymyxin B Ophthalmic is used in veterinary medicine for: FDA-approved veterinary ophthalmic ointment; Effective for feline conjunctivitis.
›What is the Oxytetracycline/Polymyxin B Ophthalmic dose for dogs?
For dogs, Oxytetracycline/Polymyxin B Ophthalmic is typically dosed as follows — FDA-approved veterinary ophthalmic ointment: undefined undefined Ophthalmic q6–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Oxytetracycline/Polymyxin B Ophthalmic dose for cats?
For cats, Oxytetracycline/Polymyxin B Ophthalmic is typically dosed as follows — Effective for feline conjunctivitis: undefined undefined Ophthalmic q6–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Oxytetracycline/Polymyxin B Ophthalmic need a prescription?
Oxytetracycline/Polymyxin B Ophthalmic is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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