Oxytetracycline inhibits bacterial protein synthesis (30S ribosomal subunit) covering gram-positive, Chlamydophila, and Mycoplasma. Polymyxin B disrupts gram-negative cell membranes. Together provide broad-spectrum coverage for ocular infections.
At a glance
Class
Ophthalmic Combination Antibiotic
Storage
Store at room temperature below 25°C
Dosing
FDA-approved veterinary ophthalmic ointment
Effective for feline conjunctivitis
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Clinical response at 5–7 daysCulture if no improvement
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
Brands
United States
Terramycin Ophthalmic
Zoetis
FAQs
Frequently asked questions
›What is Oxytetracycline/Polymyxin B Ophthalmic?
Oxytetracycline/Polymyxin B Ophthalmic is a ophthalmic combination antibiotic used in pets. Oxytetracycline inhibits bacterial protein synthesis (30S ribosomal subunit) covering gram-positive, Chlamydophila, and Mycoplasma. Polymyxin B disrupts gram-negative cell membranes. Together provide broad-spectrum coverage for ocular infections.
›What is Oxytetracycline/Polymyxin B Ophthalmic used for in pets?
Oxytetracycline/Polymyxin B Ophthalmic is used in veterinary medicine for: FDA-approved veterinary ophthalmic ointment; Effective for feline conjunctivitis.
›What is the Oxytetracycline/Polymyxin B Ophthalmic dose for dogs?
For dogs, Oxytetracycline/Polymyxin B Ophthalmic is typically dosed as follows — FDA-approved veterinary ophthalmic ointment: undefined undefined Ophthalmic q6–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Oxytetracycline/Polymyxin B Ophthalmic dose for cats?
For cats, Oxytetracycline/Polymyxin B Ophthalmic is typically dosed as follows — Effective for feline conjunctivitis: undefined undefined Ophthalmic q6–8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Oxytetracycline/Polymyxin B Ophthalmic need a prescription?
Oxytetracycline/Polymyxin B Ophthalmic is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database