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Oxytetracycline

Prescription
Tetracycline antibiotic
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
4 available
Formulations
3

Mechanism of action

Inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing attachment of aminoacyl-tRNA; bacteriostatic at therapeutic doses

At a glance

Class
Tetracycline antibiotic
Schedule
Prescription
Storage
Below 25°C, protect from light and moisture

Dosing

🐕

Dog

Susceptible bacterial infections, ehrlichiosis, leptospirosis
Dose
7.5–20 mg/kg
Route
PO, IM, IV
Frequency
BID to TID
Max dose
500 mg/dose; 1500 mg/day
Duration: 7–21 days
🐈

Cat

Susceptible bacterial infections, Mycoplasma
Dose
7.5–20 mg/kg
Route
PO, IM
Frequency
BID to TID
Max dose
250 mg/dose; 750 mg/day
Duration: 7–14 days
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Tablet — 1

Strength
250mg
Available in India
💉

Injectable solution — 1

Strength
100mg/mL
Available in India
💉

Long-acting injectable — 1

Strength
200mg/mL
Available in India

Storage

Below 25°C, protect from light and moisture

Safety

Absolute contraindications — do not use

  • Hypersensitivity to tetracyclines

Use with caution

  • Pregnancy
    Chelation reduces absorption; causes tooth discoloration in developing animals

Adverse effects

Common
GI upset
Photosensitivity
Tooth discoloration in young animals
Serious
Hepatotoxicity
Esophageal stricture (cats)
Superinfection

Monitoring parameters

Hepatic functionRenal functionSigns of photosensitivity
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

International

Terramycin
Zoetis
Liquamycin LA-200
Zoetis

India

Terramycin
Pfizer India
Oxytet-LA
Intas

FAQs

Frequently asked questions

What is Oxytetracycline?
Oxytetracycline is a tetracycline antibiotic used in pets. Inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing attachment of aminoacyl-tRNA; bacteriostatic at therapeutic doses
What is Oxytetracycline used for in pets?
Oxytetracycline is used in veterinary medicine for: Susceptible bacterial infections, ehrlichiosis, leptospirosis; Susceptible bacterial infections, Mycoplasma.
What is the Oxytetracycline dose for dogs?
For dogs, Oxytetracycline is typically dosed as follows — Susceptible bacterial infections, ehrlichiosis, leptospirosis: 7.5–20 mg/kg PO/IM/IV BID to TID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Oxytetracycline dose for cats?
For cats, Oxytetracycline is typically dosed as follows — Susceptible bacterial infections, Mycoplasma: 7.5–20 mg/kg PO/IM BID to TID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What are the side effects of Oxytetracycline?
Common: GI upset, Photosensitivity, Tooth discoloration in young animals. Serious (call your vet immediately): Hepatotoxicity, Esophageal stricture (cats), Superinfection.
Does Oxytetracycline need a prescription?
Yes. Oxytetracycline is a prescription medication and should only be administered under veterinary supervision.
When should Oxytetracycline not be used?
Do not use Oxytetracycline if: Hypersensitivity to tetracyclines.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

CDSCO approvals (India) — 2

Oxytetracycline long acting injectable
M/s Pfizer Pvt Ltd Bombay · Approved 1990- May
In the treatment of anaplasmosis and their annulata
Intra uterine infusion Oxytetracycline HCL- 500mg + Furazoilidone 500 mg + clioq
M/s Cadila Veterinary · Approved 05.07.1993
Intrauterine infusion for veterinary
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Tetracycline antibiotic).

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