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Osaterone

Prescription
Anti-Androgen / Progestogen
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Steroidal anti-androgen that competitively inhibits testosterone and DHT binding at androgen receptors and inhibits 5-alpha reductase. Reduces prostate size by 50–70% within 2 weeks. Also has progestogenic effects suppressing gonadotropin release.

At a glance

Class
Anti-Androgen / Progestogen
Schedule
Prescription
Storage
Store at room temperature below 30°C

Dosing

🐕

Dog

Licensed in EU for benign prostatic hyperplasia in intact male dogs
Dose
0.25–0.5 mg/kg
Route
PO
Frequency
q24h x 7 days per course
🐈

Cat

Feline prostatic disease is extremely rare
Dose
Route
N, A
Frequency
N/A
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature below 30°C

Safety

Monitoring parameters

Prostate size by ultrasound at 2 and 6 monthsHepatic enzymesClinical signs (straining, hematuria)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Ypozane

FAQs

Frequently asked questions

What is Osaterone?
Osaterone is a anti-androgen / progestogen used in pets. Steroidal anti-androgen that competitively inhibits testosterone and DHT binding at androgen receptors and inhibits 5-alpha reductase. Reduces prostate size by 50–70% within 2 weeks. Also has progestogenic effects suppressing gonadotropin release.
What is Osaterone used for in pets?
Osaterone is used in veterinary medicine for: Licensed in EU for benign prostatic hyperplasia in intact male dogs; Feline prostatic disease is extremely rare.
What is the Osaterone dose for dogs?
For dogs, Osaterone is typically dosed as follows — Licensed in EU for benign prostatic hyperplasia in intact male dogs: 0.25–0.5 mg/kg PO q24h x 7 days per course. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Osaterone dose for cats?
For cats, Osaterone is typically dosed as follows — Feline prostatic disease is extremely rare: undefined undefined N/A N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Osaterone need a prescription?
Yes. Osaterone is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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