Dimer of two 5-aminosalicylic acid (5-ASA) molecules linked by azo bond, cleaved by colonic bacteria releasing active 5-ASA locally. Unlike sulfasalazine, no sulfapyridine carrier — avoids sulfonamide side effects (KCS, allergy).
At a glance
Class
Aminosalicylate (5-ASA Dimer)
Storage
Store at room temperature below 25°C
Dosing
Used for colitis when sulfasalazine causes intolerable side effects (KCS, sulfon
Preferred over sulfasalazine for feline colitis (cats sensitive to salicylates a
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Clinical colitis responseStool consistency (paradoxical diarrhea)Renal function with prolonged use
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Olsalazine?
Olsalazine is a aminosalicylate (5-asa dimer) used in pets. Dimer of two 5-aminosalicylic acid (5-ASA) molecules linked by azo bond, cleaved by colonic bacteria releasing active 5-ASA locally. Unlike sulfasalazine, no sulfapyridine carrier — avoids sulfonamide side effects (KCS, allergy).
›What is Olsalazine used for in pets?
Olsalazine is used in veterinary medicine for: Used for colitis when sulfasalazine causes intolerable side effects (KCS, sulfon; Preferred over sulfasalazine for feline colitis (cats sensitive to salicylates a.
›What is the Olsalazine dose for dogs?
For dogs, Olsalazine is typically dosed as follows — Used for colitis when sulfasalazine causes intolerable side effects (KCS, sulfon: 5–10 mg/kg PO q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Olsalazine dose for cats?
For cats, Olsalazine is typically dosed as follows — Preferred over sulfasalazine for feline colitis (cats sensitive to salicylates a: 5–10 mg/kg PO q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Olsalazine need a prescription?
Yes. Olsalazine is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database