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Olopatadine Ophthalmic

Prescription
Ophthalmic Antihistamine / Mast Cell Stabilizer
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
3

Mechanism of action

Dual-action ophthalmic agent: selective H1-receptor antagonist (blocks histamine-mediated itch and vasodilation) AND mast cell stabilizer (prevents histamine, tryptase, and prostaglandin D2 release). Dual mechanism provides both acute and prophylactic benefit.

At a glance

Class
Ophthalmic Antihistamine / Mast Cell Stabilizer
Schedule
Prescription
Storage
Store at room temperature

Dosing

🐕

Dog

Used for allergic conjunctivitis and ocular allergy symptoms (rubbing, squinting
Dose
Route
Ophthalmic
Frequency
q12–24h
🐈

Cat

Used for feline allergic conjunctivitis
Dose
Route
Ophthalmic
Frequency
q12–24h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 3

Strength
Strength
Strength

Storage

Store at room temperature

Safety

Monitoring parameters

Allergic signs resolution (rubbing, discharge, hyperemia)Comfort assessment
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Patanol
Alcon
Pataday
Alcon

FAQs

Frequently asked questions

What is Olopatadine Ophthalmic?
Olopatadine Ophthalmic is a ophthalmic antihistamine / mast cell stabilizer used in pets. Dual-action ophthalmic agent: selective H1-receptor antagonist (blocks histamine-mediated itch and vasodilation) AND mast cell stabilizer (prevents histamine, tryptase, and prostaglandin D2 release). Dual mechanism provides both acute and prophylactic benefit.
What is Olopatadine Ophthalmic used for in pets?
Olopatadine Ophthalmic is used in veterinary medicine for: Used for allergic conjunctivitis and ocular allergy symptoms (rubbing, squinting; Used for feline allergic conjunctivitis.
What is the Olopatadine Ophthalmic dose for dogs?
For dogs, Olopatadine Ophthalmic is typically dosed as follows — Used for allergic conjunctivitis and ocular allergy symptoms (rubbing, squinting: undefined undefined Ophthalmic q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Olopatadine Ophthalmic dose for cats?
For cats, Olopatadine Ophthalmic is typically dosed as follows — Used for feline allergic conjunctivitis: undefined undefined Ophthalmic q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Olopatadine Ophthalmic need a prescription?
Yes. Olopatadine Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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