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Olopatadine Ophthalmic

Prescription
Ophthalmic Antihistamine / Mast Cell Stabilizer
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
3

Mechanism of action

Dual-action ophthalmic agent: selective H1-receptor antagonist (blocks histamine-mediated itch and vasodilation) AND mast cell stabilizer (prevents histamine, tryptase, and prostaglandin D2 release). Dual mechanism provides both acute and prophylactic benefit.

At a glance

Class
Ophthalmic Antihistamine / Mast Cell Stabilizer
Schedule
Prescription
Storage
Store at room temperature

Dosing

🐕

Dog

Used for allergic conjunctivitis and ocular allergy symptoms (rubbing, squinting
Dose
Route
Ophthalmic
Frequency
q12–24h
🐈

Cat

Used for feline allergic conjunctivitis
Dose
Route
Ophthalmic
Frequency
q12–24h

Formulations

💊

Other — 3

Strength
Strength
Strength

Storage

Store at room temperature

Safety

Monitoring parameters

Allergic signs resolution (rubbing, discharge, hyperemia)Comfort assessment

Interactions

No documented interactions.

Brands

Other markets

Patanol
Alcon
Pataday
Alcon

FAQs

Frequently asked questions

What is Olopatadine Ophthalmic?
Olopatadine Ophthalmic is a ophthalmic antihistamine / mast cell stabilizer used in pets. Dual-action ophthalmic agent: selective H1-receptor antagonist (blocks histamine-mediated itch and vasodilation) AND mast cell stabilizer (prevents histamine, tryptase, and prostaglandin D2 release). Dual mechanism provides both acute and prophylactic benefit.
What is Olopatadine Ophthalmic used for in pets?
Olopatadine Ophthalmic is used in veterinary medicine for: Used for allergic conjunctivitis and ocular allergy symptoms (rubbing, squinting; Used for feline allergic conjunctivitis.
What is the Olopatadine Ophthalmic dose for dogs?
For dogs, Olopatadine Ophthalmic is typically dosed as follows — Used for allergic conjunctivitis and ocular allergy symptoms (rubbing, squinting: undefined undefined Ophthalmic q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Olopatadine Ophthalmic dose for cats?
For cats, Olopatadine Ophthalmic is typically dosed as follows — Used for feline allergic conjunctivitis: undefined undefined Ophthalmic q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Olopatadine Ophthalmic need a prescription?
Yes. Olopatadine Ophthalmic is a prescription medication and should only be administered under veterinary supervision.

References

References

Textbooks & handbooks

  • Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
  • Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
  • Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
  • National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
  • The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/

Clinical guidelines & consensus

  • Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
  • American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.

Journals & peer-reviewed studies

  • Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
  • Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
  • ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control

Regulatory & approvals

  • Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/

Databases

  • Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →