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Octreotide

Prescription
Somatostatin Analog
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
2

Mechanism of action

Synthetic long-acting octapeptide analog of somatostatin that inhibits growth hormone, glucagon, insulin, gastrin, VIP, and other GI/pancreatic hormones. Reduces splanchnic blood flow. Used for insulinoma, gastrinoma, and GI hemorrhage.

At a glance

Class
Somatostatin Analog
Schedule
Prescription
Storage
Refrigerate 2–8°C; stable at room temperature up to 14 days; protect from light

Dosing

🐕

Dog

Used for insulinoma-associated hypoglycemia (inhibits insulin secretion), gastri
Dose
10–40 mcg/dog
Route
SQ, IV CRI
Frequency
q8–12h (SQ); continuous (CRI)
🐈

Cat

Limited feline data
Dose
2–4 mcg/cat
Route
SQ
Frequency
q8–12h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Refrigerate 2–8°C; stable at room temperature up to 14 days; protect from light

Safety

Monitoring parameters

Blood glucoseGI toleranceAbdominal ultrasound (gallbladder) with chronic useTumor response
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Sandostatin

FAQs

Frequently asked questions

What is Octreotide?
Octreotide is a somatostatin analog used in pets. Synthetic long-acting octapeptide analog of somatostatin that inhibits growth hormone, glucagon, insulin, gastrin, VIP, and other GI/pancreatic hormones. Reduces splanchnic blood flow. Used for insulinoma, gastrinoma, and GI hemorrhage.
What is Octreotide used for in pets?
Octreotide is used in veterinary medicine for: Used for insulinoma-associated hypoglycemia (inhibits insulin secretion), gastri; Limited feline data.
What is the Octreotide dose for dogs?
For dogs, Octreotide is typically dosed as follows — Used for insulinoma-associated hypoglycemia (inhibits insulin secretion), gastri: 10–40 mcg/dog SQ/IV CRI q8–12h (SQ); continuous (CRI). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Octreotide dose for cats?
For cats, Octreotide is typically dosed as follows — Limited feline data: 2–4 mcg/cat SQ q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Octreotide need a prescription?
Yes. Octreotide is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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