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Nystatin

Prescription
Polyene antifungal
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
4 available
Formulations
2

Mechanism of action

Binds to ergosterol in fungal cell membranes, creating pores that increase membrane permeability, leading to leakage of intracellular contents and cell death

At a glance

Class
Polyene antifungal
Schedule
Prescription
Storage
Below 25°C, protect from light and moisture

Dosing

🐕

Dog

Oral and GI candidiasis, topical fungal infections
Dose
22000–100000 IU/kg
Route
PO, topical
Frequency
TID to QID
Max dose
500000 IU/dose; 2000000 IU/day
Duration: 7–14 days or until resolved
🐈

Cat

Oral and GI candidiasis
Dose
22000–100000 IU/kg
Route
PO, topical
Frequency
TID to QID
Max dose
500000 IU/dose; 2000000 IU/day
Duration: 7–14 days or until resolved
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

🧴

Oral suspension — 1

Strength
100,000 IU/mL
Available in India
💊

Tablet — 1

Strength
500,000 IU
Available in India

Storage

Below 25°C, protect from light and moisture

Safety

Absolute contraindications — do not use

  • Hypersensitivity to nystatin
    Not absorbed systemically from intact GI tract

Adverse effects

Common
GI upset
Vomiting
Diarrhea
Serious
Hypersensitivity reactions (rare)

Monitoring parameters

Clinical resolution of lesionsAppetite and GI signs
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

International

Mycostatin
Bristol-Myers Squibb
Panalog (combination)
Novartis

India

Nystatin Oral Suspension
Glenmark
Mycostatin
Cadila

FAQs

Frequently asked questions

What is Nystatin?
Nystatin is a polyene antifungal used in pets. Binds to ergosterol in fungal cell membranes, creating pores that increase membrane permeability, leading to leakage of intracellular contents and cell death
What is Nystatin used for in pets?
Nystatin is used in veterinary medicine for: Oral and GI candidiasis, topical fungal infections; Oral and GI candidiasis.
What is the Nystatin dose for dogs?
For dogs, Nystatin is typically dosed as follows — Oral and GI candidiasis, topical fungal infections: 22000–100000 IU/kg PO/topical TID to QID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Nystatin dose for cats?
For cats, Nystatin is typically dosed as follows — Oral and GI candidiasis: 22000–100000 IU/kg PO/topical TID to QID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What are the side effects of Nystatin?
Common: GI upset, Vomiting, Diarrhea. Serious (call your vet immediately): Hypersensitivity reactions (rare).
Does Nystatin need a prescription?
Yes. Nystatin is a prescription medication and should only be administered under veterinary supervision.
When should Nystatin not be used?
Do not use Nystatin if: Hypersensitivity to nystatin.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Polyene antifungal).

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Binds to ergosterol in fungal cell membranes, creating pores that disrupt membrane integrity and cause cell death
dogcat
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